Novel applications of physical autocatalysis.
Novel applications of physical autocatalysis.
复制标题
物理自催化的新应用。
DOI：
10.1007/s11084-015-9404-y
复制
发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Bissette AJ
中科院分区：
文献类型：
--
作者：
Bissette AJ
胶束和囊泡的自催化自我复制已经研究了几十年。这些系统是某些原始细胞模型的重要组成部分，也是生命如何从简单化学物质的混合物开始的一些模型的重要组成部分。在这里，我们讨论了我们最近描述的自催化系统，其中自复制胶束是由成键反应驱动的。这些系统通过共价键形成在分子水平上和通过自发自组装成功能性聚集体在超分子水平上产生增加的复杂性。这为研究自我复制脂质聚集体在前生物世界中的潜在作用提供了概念基础。
The autocatalytic self-reproduction of micelles and vesicles has been studied for several decades. These systems are vital components of certain protocell models and some models for how life may have begun from mixtures of simple chemicals. Here we discuss our recently described autocatalytic systems where self-reproducing micelles are driven by bond-forming reactions. These systems generate increased complexity on both the molecular level, through covalent bond formation, and the supramolecular level, through spontaneous self-assembly into functional aggregates. This provides the conceptual basis for novel studies of the potential roles of self-reproducing lipid aggregates in the prebiotic world.