Prior fractures are common in patients with subsequent hip fractures
Prior fractures are common in patients with subsequent hip fractures
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DOI：
10.1097/blo.0b013e3180534269
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发表时间：
2007-08-01
影响因子：
4.2
通讯作者：
Fitzpatrick, Lorraine A.
中科院分区：
文献类型：
--
作者：
Edwards, Beatrice J.;Bunta, Andrew D.;Fitzpatrick, Lorraine A.
对有骨折史的患者进行骨质疏松治疗，可能会使未来骨折的风险降低50%。我们回顾性回顾了632例髋部骨折患者，以评估(1)髋部骨折中既往骨折的发生率，(2)既往骨折是否导致骨质疏松治疗的增加，以及(3)既往骨折后骨质疏松治疗的成本效用。从2000年1月至2001年6月，这些病人在三家医院接受治疗，其中514名（80%）是妇女。轻度创伤性骨折被定义为在站立、行走或从低于4英尺的高度跌落时导致的骨折。282例（45%）偶发性髋部骨折患者描述了先前的轻微创伤性骨折。43名（13%）女性和3名（5%）男性被诊断为骨质疏松症。107例（17%）发生髋部骨折为第二次髋部骨折。先前的轻微创伤骨折并没有增加骨质疏松症的治疗。假设通过药物治疗骨折风险降低50%，治疗282例既往轻度创伤性骨折患者将节省350万美元。
Treating osteoporosis in patients with prior fractures potentially results in a 50% reduction of risk of future fractures. We retrospectively reviewed 632 patients with incident hip fractures to evaluate (1) the prevalence of prior fractures in incident hip fractures, (2) whether prior fractures led to an increase in the treatment of osteoporosis, and (3) the cost utility of osteoporosis treatment after a prior fracture. The patients were treated at three hospitals from January 2000 to June 2001 and 514 (80%) were women. A minimal trauma fracture was defined as a fracture resulting from a fall while standing or walking or falling from a height less than 4 feet. Two hundred eighty-two patients (45%) with incident hip fractures described a prior minimal trauma fracture. Osteoporosis was diagnosed in 43 (13%) women and three (5%) men. In 107 cases (17%), the incident hip fracture was the second hip fracture. A prior minimal trauma fracture did not increase treatment for osteoporosis. Presuming a 50% reduction in fracture risk with medications, treating the 282 patients with prior minimal trauma fracture would have resulted in a savings of $3.5 million.