Ratiometric fluorescence sensing of bacterial lipopolysaccharide by a simple combination of a cationic dye and an anionic dye

Ratiometric fluorescence sensing of bacterial lipopolysaccharide by a simple combination of a cationic dye and an anionic dye
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DOI:
10.1016/j.snb.2012.03.017
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发表时间:
2012-05
影响因子:
8.4
通讯作者:
Wanhua Lei;Guoyu Jiang;Qianxiong Zhou;Yuan-jun Hou;Bao-wen Zhang;Xuexin Cheng;Xuesong Wang
Wanhua Lei;Guoyu Jiang;Qianxiong Zhou;Yuan-jun Hou;Bao-wen Zhang;Xuexin Cheng;Xuesong Wang
中科院分区:
化学1区
文献类型:
--
作者:
Wanhua Lei;Guoyu Jiang;Qianxiong Zhou;Yuan-jun Hou;Bao-wen Zhang;Xuexin Cheng;Xuesong Wang

文献摘要

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在水溶液中,两个阳离子荧光团珊瑚烯和一个阴离子荧光团9,10-蒽二基-双(亚甲基)二丙二酸可形成2:1的离子对络合物。在细菌脂多糖存在的情况下,该复合物沿着解离,荧光谱发生显着变化,用于以比率荧光模式灵敏地、选择性地检测细菌脂多糖,检测限低至亚微摩尔浓度。
Two cationic fluorophore coralyne and one anionic fluorophore 9,10-anthracenediyl-bis(methylene)dimalonic acid can form 2:1 ion pair complex in aqueous solutions. The complex experiences dissociation along with significant changes in fluorescence profile in the presence of bacterial lipopolysaccharide, which is utilized to sensitively and selectively detect the bacterial lipopolysaccharide in ratiometric fluorescence mode with the detection limit down to submicromolar concentration.