Copper/TEMPO catalysed synthesis of nitriles from aldehydes or alcohols using aqueous ammonia and with air as the oxidant
Copper/TEMPO catalysed synthesis of nitriles from aldehydes or alcohols using aqueous ammonia and with air as the oxidant
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DOI：
10.1039/c3cc42231c
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发表时间：
2013-01-01
影响因子：
4.9
通讯作者：
Muldoon, Mark J.
中科院分区：
文献类型：
--
作者：
Dornan, Laura M.;Cao, Qun;Muldoon, Mark J.
铜/TEMPO 催化剂可用于使用氨水从醛或醇制备腈。我们开发了易于使用的方法，使标准玻璃器皿能够使用空气作为 O-2 源。进一步表明，在加压反应器中的较高温度和限氧条件（8% O-2）下，可以采用1 mol%的催化剂负载量。
Copper/TEMPO catalysts can be used to prepare nitriles from aldehydes or alcohols using aqueous ammonia. Readily accessible methods were developed that enable standard glassware to be used with air as the source of O-2. It was further shown that, at higher temperatures in a pressurised reactor under limiting oxygen conditions (8% O-2), catalyst loadings of 1 mol% could be employed.