COAGULATION ACTIVATION IN TYPE-2 DIABETES-MELLITUS - THE HIGHER CORONARY RISK OF FEMALE DIABETIC-PATIENTS
COAGULATION ACTIVATION IN TYPE-2 DIABETES-MELLITUS - THE HIGHER CORONARY RISK OF FEMALE DIABETIC-PATIENTS
复制标题
DOI：
10.1111/j.1464-5491.1995.tb00532.x
复制
发表时间：
1995-06-01
影响因子：
3.5
通讯作者：
PAN, WH
中科院分区：
文献类型：
--
作者：
CHAN, P;PAN, WH
糖尿病患者的血栓形成倾向是一种公认的现象，它构成了冠心病的额外风险。本研究包括1980名中国人（男性835名，女性1145名）;年龄范围：45 - 69岁，包括280名2型糖尿病患者（男性125名，女性155名）。测定的止血参数为纤维蛋白原、凝血酶原时间、活化部分凝血活酶时间（APTT）、凝血因子Vile、凝血因子Ville、抗凝血酶III和纤溶酶原。与对照组相比，男性糖尿病患者的APTT明显缩短（25.6 +/- 3.7 vs 27.5 +/- 3.6 s，p
Thrombophilia in diabetic patients is a well-recognized phenomenon which constitutes an additional risk of coronary heart disease. This study included 1980 ethnic Chinese people (835 male, 1145 female); age range: 45 to 69 years, including 280 Type 2 diabetic patients (male 125, female 155). Haemostatic parameters measured were fibrinogen, prothrombin time, activated partial thromboplastin time (APTT), factor Vile, factor Ville, antithrombin III, and plasminogen. Compared with a control group, male diabetic patients showed significantly shorter APTT (25.6 +/- 3.7 vs 27.5 +/- 3.6 s, p