ALKALINE-PHOSPHATASE OF THE CALF INTESTINE HYDROLYZES PHOSPHOLIPIDS

ALKALINE-PHOSPHATASE OF THE CALF INTESTINE HYDROLYZES PHOSPHOLIPIDS
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DOI:
10.1016/0014-5793(85)80822-x
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发表时间:
1985-01-01
期刊:
影响因子:
3.5
通讯作者:
HORN, A
HORN, A
中科院分区:
生物学3区
文献类型:
--
作者:
EHLE, H;MULLER, E;HORN, A

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Pure alkaline phosphatase of the calf intestine is able to hydrolyze phosphatidylinositol 4,5-diphosphate (TPI) to phosphatidylinositol and Piand to dephosphorylate phosphatidic acid. This phosphomonoesterase activity shows a considerably high specifie activity when an incubation medium at neutral pH containing 3 mM deoxycholate is used. The activity is inhibited by low concentrations of Ca2+. The enzyme has no detectable phosphodiesterase activity under the conditions tested.