Current trends in the prevalence of Cryptococcus gattii in the United States and Canada.
Current trends in the prevalence of Cryptococcus gattii in the United States and Canada.
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DOI：
10.2147/idr.s57686
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发表时间：
2015
影响因子：
3.9
通讯作者：
Kidd SE
中科院分区：
文献类型：
--
作者：
Espinel-Ingroff A;Kidd SE
本文献综述提供了除不列颠哥伦比亚省（BC）疫情（1999-2013年）以外加拿大和美国（US）的格特隐球菌感染发生率。通过文献检索，获得了C.自从C. gattii在BC爆发。文献表明：i）虽然C.这两个国家继续报告格特感染病例，初步确认的格特感染总数。在加拿大和美国，gattii感染可能正在减少（2012年各约23例，2013年分别约17例和20例）; ii）C. gattii基因型分布具有地域依赖性; gattii比以前预期的更频繁地从免疫受损宿主的感染（包括获得性免疫缺陷综合征[AIDS]感染）中分离; iv）尽管肺病比C.在新型隐球菌感染的患者中，也报告了中枢神经系统疾病。加提。
The incidence of Cryptococcus gattii infections in both Canada and the United States (US) is provided in this literature review beyond the British Columbia (BC) outbreak (1999–2013). Based on a search of the literature, case reports of C. gattii human infections including the prevalent molecular genotypes causing these infections in both Canada and the US have been documented since the C. gattii outbreak in BC. The literature reveals that: i) although C. gattii infections continue to be reported in both countries, the preliminary overall number of confirmed C. gattii infections may be decreasing in both Canada and the US (~23 cases each in 2012 versus ~17 and 20 cases, respectively in 2013); ii) C. gattii genotype distribution is region-dependent; iii) C. gattii is more frequently isolated from infections in the immunocompromised host (including acquired immune deficiency syndrome [AIDS] infection) than previously expected; iv) although pulmonary disease is higher than in C. neoformans infections, central nervous system disease is also reported among patients infected with C. gattii.