The addition of nanostructured hydroxyapatite to an experimental adhesive resin
The addition of nanostructured hydroxyapatite to an experimental adhesive resin
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DOI：
10.1016/j.jdent.2013.01.001
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发表时间：
2013-04-01
影响因子：
4.4
通讯作者：
Werner Samuel, Susana Maria
中科院分区：
文献类型：
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作者：
Branco Leitune, Vicente Castelo;Collares, Fabricio Mezzomo;Werner Samuel, Susana Maria
目的：制备了纳米结构羟基磷灰石（HA（纳米）），并评估了其纳入粘合resin.Methods的影响：HA（纳米）是由火焰为基础的过程，并通过扫描电子显微镜进行了表征。评价了表面积、粒径、显微拉曼光谱和细胞毒性。有机相通过混合50重量% Bis-GMA，25重量% TEGDMA和25重量% HEMA。HA（纳米）以七种不同的浓度添加：0、0.5、1、2、5、10和20重量%。结合羟基磷灰石的粘合树脂的射线不透性，转化度，弯曲强度，在溶剂中的软化和微剪切粘结强度进行了评价。除了溶剂软化（配对t检验）和细胞毒性（双因素方差分析和Bonferroni）外，数据通过单因素方差分析和Tukey事后检验（α = 0.05）进行分析。不透射线性值与1 mm铝的不透射线性值无差异。转化率范围为52.2 - 63.8%。HA（纳米）的掺入不影响弯曲强度，其范围为123.3至143.4 MPa。随着HA（纳米）浓度的增加，浸泡在溶剂中后的显微硬度的降低百分比变得较低。纳米结构羟基磷灰石的加入量为2%时，微剪切强度明显高于对照组（p < 0.05）。结论：纳米结构羟基磷灰石的加入量为2%时，粘接效果最好。临床意义：纳米结构羟基磷灰石的引入提高了粘接性能，可能是一种有前途的粘接树脂填料。(C)2013爱思唯尔有限公司保留所有权利。
Objectives: Was produced nanostructured hydroxyapatite (HA(nano)) and evaluated the influence of its incorporation in an adhesive resin.Methods: HA(nano) was produced by a flame-based process and was characterized by scanning electron microscopy. The surface area, particle size, micro-Raman and cytotoxicity were evaluated. The organic phase was formulated by mixing 50 wt.% Bis-GMA, 25 wt.% TEGDMA, and 25 wt.% HEMA. HA(nano) was added at seven different concentrations: 0; 0.5; 1; 2; 5; 10 and 20 wt.%. Adhesive resins with hydroxyapatite incorporation were evaluated for their radiopacity, degree of conversion, flexural strength, softening in solvent and microshear bond strength. The data were analyzed by one-way ANOVA and Tukey's post hoc test (alpha = 0.05), except for softening in solvent (paired t-test) and cytotoxicity (two-way ANOVA and Bonferroni).Results: HA(nano) presented 15.096 m(2)/g of specific surface area and a mean size of 26.7 nm. The radiopacity values were not different from those of 1-mm aluminium. The degree of conversion ranged from 52.2 to 63.8%. The incorporation of HA(nano) did not influence the flexural strength, which ranged from 123.3 to 143.4 MPa. The percentage of reduction of the microhardness after immersion in the solvent became lower as the HA(nano) concentration increased. The addition of 2% nanostructured hydroxyapatite resulted in a higher value of microshear bond strength than the control group (p < 0.05).Conclusions: The incorporation of 2% of nanostructured hydroxyapatite into an adhesive resin presented the best results. Clinical significance: The incorporation of nanostructured hydroxyapatite increases the adhesive properties and may be a promising filler for adhesive resin. (C) 2013 Elsevier Ltd. All rights reserved.