An introduction to instrumental variables for epidemiologists

An introduction to instrumental variables for epidemiologists
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DOI:
10.1093/ije/29.4.722
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发表时间:
2000-08-01
影响因子:
7.7
通讯作者:
Greenland, S
Greenland, S
中科院分区:
医学1区
文献类型:
--
作者:
Greenland, S

文献摘要

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工具变量(IV)方法发明于70多年前,但在流行病学中仍然不常见。在过去的十年左右,非参数版本的IV方法已经出现,连接IV方法的因果关系和测量误差模型在流行病学应用中的重要性。本文介绍了这些发展,说明了IV方法的应用程序,非参数调整不遵守随机试验。
Instrumental-variable (IV) methods were invented over 70 years ago, but remain uncommon in epidemiology. Over the past decade or so, non-parametric versions of IV methods have appeared that connect IV methods to causal and measurement-error models important in epidemiological applications. This paper provides an introduction to those developments, illustrated by an application of IV methods to non-parametric adjustment for non-compliance in randomized trials.