A review of anti-D treatment of childhood idiopathic thrombocytopenic purpura
A review of anti-D treatment of childhood idiopathic thrombocytopenic purpura
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DOI：
10.1002/pbc.20996
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发表时间：
2006-10-15
影响因子：
3.2
通讯作者：
Hasle, Henrik
中科院分区：
文献类型：
--
作者：
Kjaersgaard, Mimi;Hasle, Henrik
Treatment of childhood idiopathic thrombocytopenic purpura is still an area of controversy. We reviewed the literature on anti-D treatment. Most studies used intravenous anti-D. Single doses of 50 mu g/kg increased the platelet count to >= 20 x 10(9)/L in 70% of the children within 3 days. intravenous anti-D seems safe in classic childhood ITP although hemolysis and occasionally renal failure may be of concern. A few studies reported intramuscularly or subcutaneously administered anti-D. Further studies on the optimal dose and route of administration of anti-D are warranted. Pediatr Blood Cancer 2006;47:717-720. (c) 2006 Wiley-Liss, Inc.
