Air pollution exposure and self-reported cardiovascular disease
Air pollution exposure and self-reported cardiovascular disease
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DOI：
10.1016/j.envres.2009.01.001
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发表时间：
2009-07-01
影响因子：
8.3
通讯作者：
Parker, Jennifer D.
中科院分区：
文献类型：
--
作者：
Johnson, Derek;Parker, Jennifer D.
背景：研究表明，细颗粒物浓度（PM2.5）的增加可能与心血管疾病的增加有关。大约25%的30岁及以上的美国成年人报告患有心脏病或高血压，暴露在空气污染中可能会对公众健康产生重大影响。这项研究利用一项大型全国性调查的数据，研究了PM2.5与自我报告的高血压和心脏病患病率之间的关系。研究设计：将1999年至2005年参加全国健康访谈调查（NHIS）的30岁及以上成年人与美国环境保护署的年度PM2.5数据（N = 132,224）联系起来。年度空气质量估计值的平均值来自于被调查者居住街区20英里范围内的监测仪。在两次或两次以上不同的场合被健康专业人员告知患有高血压的受访者被定义为高血压。心脏病被定义为对NHIS关于心脏病的三个问题中的一个或多个回答“是”。结果：PM2.5暴露量增加10 μ g/m(3)与高血压（校正优势比（OR） 1.05, 95%置信区间（CI） 1.00-1.10）和心脏病（1.08 95%置信区间（CI） 1.00-1.16）风险小幅升高相关。PM2.5与高血压之间的关联在非西班牙裔白人成年人中发现（OR 1.10 95% CI 1.04-1.17），但在非西班牙裔黑人或西班牙裔成年人中没有发现。结论：本研究的发现补充了其他研究的结果，表明PM2.5对心血管健康有不利影响。我们的结果与其他研究一致，表明PM2.5暴露与心血管疾病之间存在很小的关联。(C) 2009爱思唯尔公司版权所有。
Background: Studies suggest that increases of fine particle concentrations (PM2.5) could be linked with a rise in cardiovascular disease. With approximately 25% of American adults aged 30 and older reporting having either heart disease or hypertension it is possible that exposure to air pollution could have significant public health consequences. This study examined the relationship between PM2.5 and the prevalence of self-reported hypertension and heart disease using data from a large nation-wide survey.Study design: Adults, 30 years of age or older, who participated in the National Health Interview Survey (NHIS) from 1999 to 2005 were linked to annual PM2.5 data from the US Environmental Protection Agency (N = 132,224). Annual air quality estimates were averaged from monitors within 20 miles of the respondent's residential block group. Respondents who reported being told they had hypertension by a health professional on two or more separate occasions were defined as hypertensive. Heart disease was defined as answering, "yes" to one or more of three NHIS questions on heart disease.Results: A 10 mu g/m(3) increase in PM2.5 exposure was associated with a small elevated risk of hypertension (adjusted odds ratio (OR) 1.05, 95% confidence interval (CI) 1.00-1.10) risk of heart disease (1.08 95% CI 1.00-1.16). The association between PM2.5 and hypertension was found in non-Hispanic white adults (OR 1.10 95% CI 1.04-1.17) but not in non-Hispanic black or Hispanic adults.Conclusions: Findings from this study complement those from other studies and indicate that PM2.5 adversely affects cardiovascular health. Our results are consistent with other studies in showing a small association between exposure to PM2.5 and cardiovascular outcomes. (C) 2009 Elsevier Inc. All rights reserved.