Advances in functional X-ray imaging techniques and contrast agents.

Advances in functional X-ray imaging techniques and contrast agents.
复制标题

DOI:
10.1039/c2cp41858d
复制
发表时间:
2012-10-21
期刊:
Physical chemistry chemical physics : PCCP
影响因子:
--
通讯作者:
Anker JN
Anker JN
中科院分区:
其他
文献类型:
--
作者:
Chen H;Rogalski MM;Anker JN

文献摘要

参考文献

被引文献

相似文献

自1895年发现以来,X射线一直用于厚生物标本的非侵入性高分辨率成像。它们广泛用于骨、金属植入物和软组织中的腔的结构成像。最近,出现了一些新的对比度方法,这些方法将X射线的生物医学应用扩展到功能和结构成像。这些技术有望大大提高我们研究原位生物化学和疾病病理学的能力。在这篇综述中,我们讨论了如何X射线吸收,X射线荧光和X射线激发的光致发光可用于生理,元素和分子成像的脉管系统,肿瘤,药物分布,和表面的植入物。将讨论用光学指示剂检测的内源性元素、外源性标签和分析物的成像。
X-rays have been used for non-invasive high-resolution imaging of thick biological specimens since their discovery in 1895. They are widely used for structural imaging of bone, metal implants, and cavities in soft tissue. Recently, a number of new contrast methodologies have emerged which are expanding X-ray’s biomedical applications to functional as well as structural imaging. These techniques are promising to dramatically improve our ability to study in situ biochemistry and disease pathology. In this review, we discuss how X-ray absorption, X-ray fluorescence, and X-ray excited optical luminescence can be used for physiological, elemental, and molecular imaging of vasculature, tumours, pharmaceutical distribution, and the surface of implants. Imaging of endogenous elements, exogenous labels, and analytes detected with optical indicators will be discussed.
DOI: 10.1088/0031-9155/55/3/007
发表时间: 2010-02-01
影响因子: 3.5
作者:
Cheong, Seong-Kyun;Jones, Bernard L.;Cho, Sang Hyun
通讯作者: Cho, Sang Hyun
DOI: 10.1118/1.3457332
发表时间: 2010-08-01
期刊: MEDICAL PHYSICS
影响因子: 3.8
作者:
Carpenter, C. M.;Sun, C.;Xing, L.
通讯作者: Xing, L.
DOI: 10.1103/revmodphys.44.716
发表时间: 1972-01-01
影响因子: 44.1
作者:
BAMBYNEK, W;SWIFT, CD;FINK, RW
通讯作者: FINK, RW
DOI: 10.2214/ajr.181.5.1811197
发表时间: 2003-11-01
影响因子: 5
作者:
Carroll, FE;Mendenhall, MH;Waters, JW
通讯作者: Waters, JW
DOI: 10.1148/115.2.431
发表时间: 1975-01-01
期刊: RADIOLOGY
影响因子: 19.7
作者:
ATKINS, HL;FAIRCHILD, RG;GREENBERG, D
通讯作者: GREENBERG, D