Moving and positioning the endolysosomal system.

Moving and positioning the endolysosomal system.
复制标题

DOI:
10.1016/j.ceb.2017.01.008
复制
发表时间:
2017-08
影响因子:
7.5
通讯作者:
Neefjes J
Neefjes J
中科院分区:
生物学2区
文献类型:
--
作者:
Bonifacino JS;Neefjes J

文献摘要

参考文献

被引文献

相似文献

内溶体系统非常有活力,但高度组织化。内溶酶体细胞器的时空分布依赖于由运动蛋白和动力蛋白等微管马达和肌球蛋白马达驱动的运输。最近人们认识到,与发动机的相互作用是通过与其他细胞器,特别是内质网(ER)的接触来控制的。内质网还通过一个复杂的系留蛋白系统控制核周区域内溶酶体细胞器的浓度,以及它们的分裂和融合。动态的相互作用是双向的,因为与内小体的接触可以影响内质网和过氧化物体的运动。因此,不应再孤立地研究内溶酶体细胞器的动力学,而应在整个内膜系统的背景下进行研究。
The endolysosomal system is extremely dynamic, yet highly organized. The spatiotemporal distribution of endolysosomal organelles depends on transport driven by microtubule motors such as kinesins and dynein, and by actin-based myosin motors. It has recently become appreciated that interactions with motors are controlled by contacts with other organelles, particularly the endoplasmic reticulum (ER). The ER also controls the concentration of endolysosomal organelles in the perinuclear area, as well as their fission and fusion, through a complex system of tethering proteins. Dynamic interactions go both ways, as contacts with endosomes can influence the movement of the ER and peroxisomes. The dynamics of endolysosomal organelles should thus no longer be studied in isolation, but in the context of the whole endomembrane system.
Rab7在分泌颗粒在细胞毒性T淋巴细胞中的运动中的作用。
DOI: 10.1111/j.1600-0854.2011.01194.x
发表时间: 2011-07
期刊: Traffic (Copenhagen, Denmark)
影响因子: --
作者:
Daniele T;Hackmann Y;Ritter AT;Wenham M;Booth S;Bossi G;Schintler M;Auer-Grumbach M;Griffiths GM
通讯作者: Griffiths GM
DOI: 10.1083/jcb.201505086
发表时间: 2015-12-07
期刊: The Journal of cell biology
影响因子: --
作者:
Guimaraes SC;Schuster M;Bielska E;Dagdas G;Kilaru S;Meadows BR;Schrader M;Steinberg G
通讯作者: Steinberg G
DOI: 10.1083/jcb.201408056
发表时间: 2015-02-02
期刊: The Journal of cell biology
影响因子: --
作者:
Bentley M;Decker H;Luisi J;Banker G
通讯作者: Banker G
DOI: 10.1038/srep08238
发表时间: 2015-02-04
期刊: Scientific reports
影响因子: 4.6
作者:
Ishida M;Ohbayashi N;Fukuda M
通讯作者: Fukuda M
DOI: 10.1242/jcs.101212
发表时间: 2012-06-01
影响因子: 4
作者:
Baumann, Sebastian;Pohlmann, Thomas;Feldbruegge, Michael
通讯作者: Feldbruegge, Michael