The EMBL nucleotide sequence database
The EMBL nucleotide sequence database
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DOI：
10.1093/nar/gkh120
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发表时间：
2004-01-01
影响因子：
14.9
通讯作者：
Apweiler, R
中科院分区：
文献类型：
--
作者：
Kulikova, T;Aldebert, P;Apweiler, R
欧洲生物信息学研究所（EBI）维护的EMBL核苷酸序列数据库（http:// www.ebi.ac.uk/embl/）整合、组织和分发来自公共来源的核苷酸序列。该数据库是与DDBJ（日本）和GenBank（美国）国际合作的一部分。每天在协作数据库之间交换数据，以实现最佳同步。基于网络的工具Webin是个人提交核苷酸序列的首选系统，包括第三方注释（TPA）和比对数据。自动提交程序用于提交来自大型基因组测序中心和欧洲专利局的数据。数据库每季度发布一次。最新的数据收集可以通过FTP，电子邮件和WWW接口访问。EBI的序列检索系统（SRS）集成并连接了主要的核苷酸和蛋白质数据库以及许多其他专业分子生物学数据库。对于序列相似性搜索，可以使用多种工具（例如FASTA和BLAST），这些工具允许外部用户将自己的序列与EMBL核苷酸序列数据库、数据库的完整基因组成分部分、WGS数据集和其他数据库中的数据进行比较。所有可用的资源都可以通过EBI主页http://www.ebi.ac.uk访问。
The EMBL Nucleotide Sequence Database (http:// www.ebi.ac.uk/embl/)), maintained at the European Bioinformatics Institute (EBI), incorporates, organizes and distributes nucleotide sequences from public sources. The database is a part of an international collaboration with DDBJ (Japan) and GenBank (USA). Data are exchanged between the collaborating databases on a daily basis to achieve optimal synchrony. The web-based tool, Webin, is the preferred system for individual submission of nucleotide sequences, including Third Party Annotation (TPA) and alignment data. Automatic submission procedures are used for submission of data from large-scale genome sequencing centres and from the European Patent Office. Database releases are produced quarterly. The latest data collection can be accessed via FTP, email and WWW interfaces. The EBI's Sequence Retrieval System (SRS) integrates and links the main nucleotide and protein databases as well as many other specialist molecular biology databases. For sequence similarity searching, a variety of tools (e.g. FASTA and BLAST) are available that allow external users to compare their own sequences against the data in the EMBL Nucleotide Sequence Database, the complete genomic component subsection of the database, the WGS data sets and other databases. All available resources can be accessed via the EBI home page at http://www.ebi.ac.uk.