Pattern of antibiotic use in the community: Non-adherence and self-prescription rates in an Italian urban population
Pattern of antibiotic use in the community: Non-adherence and self-prescription rates in an Italian urban population
复制标题
DOI：
10.3892/mmr.2012.818
复制
发表时间：
2012-05-01
影响因子：
3.4
通讯作者：
Mistretta, A.
中科院分区：
文献类型：
--
作者：
Grosso, G.;Marventano, S.;Mistretta, A.
本研究的目的是评估意大利城市社区环境中抗生素使用的模式，并确定影响其使用依从性的因素。通过使用基于问卷的调查，我们收集了1，269个访谈，并对过去12个月内最后一个抗生素疗程的患者（956名受试者）进行了分析。在报告未按照处方接受最后一个抗生素疗程的受试者中，14.7%提前停止治疗，5.4%调整剂量，5%改变处方抗生素。大约23%的受试者声称他们自行处方抗生素。调整所有协变量后，自我处方抗生素的主要预测因素是年龄较小，女性和较高的社会经济和教育地位。相反，低教育和社会经济地位与不遵守医生指示的风险较高相关。这项研究的结果评估了不良抗生素服用行为的普遍模式，并为了解未来控制抗生素使用和滥用的教育活动的目标提供了重要的启示。
The aim of the present study was to assess the pattern of antibiotic use in a community setting of an urban area of Italy and identify factors that affect adherence to their use. By using a questionnaire-based survey, we collected 1,269 interviews and performed analysis on those patients who had their last course of antibiotic within the past 12 months (956 subjects). Among the subjects reporting that they had not followed their last antibiotic course as prescribed, 14.7% stopped therapy early, 5.4% modified the dosage, and;5% changed the prescribed antibiotic. Approximately 23% of the subjects declared that they self-prescribed antibiotics. After adjusting for all covariates, major predictors for the self-prescription of antibiotics were younger age, female gender and higher socioeconomic and educational status. Conversely, both low educational and socioeconomic status were associated with a higher risk of non-adherence to physician indications. The findings of this study assessed the widespread pattern of poor antibiotic-taking behavior and provides important implications for understanding the targets of future educational campaigns to control the use and misuse of antibiotics.