Myocardial ischemia and clinical applications of positron emission tomography.
Myocardial ischemia and clinical applications of positron emission tomography.
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心肌缺血与正电子发射断层扫描的临床应用。
DOI：
10.1016/0002-9149(89)90734-0
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Schelbert,HR
中科院分区：
文献类型：
--
作者：
Schelbert,HR
正电子发射断层扫描(PET)可以无创地研究和量化人体心肌局部血流和代谢的速率。在心肌缺血时，正电子发射计算机断层扫描能识别功能障碍心肌中活性的存在和程度，并将其与不可逆转的缺血损伤和瘢痕组织形成区分开来。由于代谢标记物已被证明比传统诊断方法更准确和可靠地识别生存能力，PET在表征缺血性损伤的严重程度和程度以及为急性或慢性冠状动脉疾病患者分配最有效的治疗方面变得越来越有用。
Positron emission tomography (PET) uniquely permits the noninvasive study and quantification of regional rates of blood flow and metabolism in human myocardium. In myocardial ischemia, PET identifies the presence and extent of viability in dysfunctional myocardium and distinguishes it from irreversible ischemic injury and scar tissue formation. Because metabolic markers have proved more accurate and reliable for identifying viability than conventional diagnostic approaches, PET has become increasingly useful for characterizing the severity and extent of an ischemic injury and for assigning patients with acute or chronic coronary artery disease to the most efficacious treatment.