MOOREN ULCER AFTER PENETRATING KERATOPLASTY

MOOREN ULCER AFTER PENETRATING KERATOPLASTY
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DOI:
10.1016/s0002-9394(14)74169-8
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发表时间:
1987-01-01
影响因子:
4.2
通讯作者:
FOOS, RY
FOOS, RY
中科院分区:
医学1区
文献类型:
--
作者:
MONDINO, BJ;HOFBAUER, JD;FOOS, RY

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假性瞳孔大疱性角膜病变穿透性角膜移植术17个月后,患者出现严重疼痛和周围角膜溃疡,具有典型的摩尔氏溃疡的临床表现。我们进行了一个10毫米的穿透性角膜移植术,从先前放置的移植物的上缘延伸到下角膜巩膜边缘,以覆盖溃疡的角膜。手术切除组织的组织病理学检查显示,周围角膜溃疡几乎延伸到整个间质厚度,溃疡附近的供体角膜间质浸润淋巴细胞、浆细胞和中性粒细胞。邻近角膜溃疡周围的结膜内充盈浆细胞,并可见淋巴细胞和中性粒细胞。
Seventeen months after penetrating keratoplasty for pseudophakic bullous keratopathy, a patient developed severe pain and a peripheral corneal ulcer that had the characteristic clinical appeearance of a Mooren''s ulcer. We performed a 10-mm penetrating keratoplasty that extended from the superior margin of the previously placed graft to the inferior corneoscleral limbus to encompass the ulcerated cornea. Histopathologic examination of tissue removed at surgery disclosed that the peripheral corneal ulcer extended nearly through the entire stromal thickness and that the donor corneal stroma adjacent to the ulcer was infiltrated with lymphocytes, plasma cells, and neutrophils. The conjunctiva adjacent to the peripheral corneal ulcer was packed with plasma cells and also showed some lymphocytes and neutrophils.