Thyroid Fine Needle Aspiration Cytology: Current and Future - Proposal of A New Diagnostic System for Reporting Thyroid Cytology
Thyroid Fine Needle Aspiration Cytology: Current and Future - Proposal of A New Diagnostic System for Reporting Thyroid Cytology
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甲状腺细针抽吸细胞学：当前和未来 - 报告甲状腺细胞学的新诊断系统的提议
DOI：
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发表时间：
2015
期刊：
影响因子：
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通讯作者：
T. Takano
中科院分区：
文献类型：
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作者：
K. Kakudo;K. Kameyama;T. Takano
甲状腺细胞学中最重要的问题之一是文献中诊断类别比例、切除率和恶性风险的显著差异。除这一问题外，本研究还观察到东西方细胞病理学家在乳头状甲状腺癌的形态标准上存在显著差异，应予以标准化。此外，本课题组等人最近提出的甲状腺肿瘤分类中的交界性肿瘤类别尚未在2004年版WHO肿瘤分类中确立。将交界性甲状腺肿瘤引入甲状腺肿瘤分类系统需要建立细胞学分类。本文提出了一种新的甲状腺FNA细胞学报告系统，该系统采用了交界性病变的分类，并阐述了分子检测的最新进展。该诊断系统包括新的甲状腺细胞学术语和乳头状癌和滤泡性腺瘤/滤泡性癌家族的亚型分类。因此，这些诊断类别将不再是灰色地带或不确定的，借助分子测试为专利的临床管理提供明确的指导。
One of the most significant issues in thyroid cytology is the marked differences in diagnostic category proportion, resection rate, and malignant risk in literature. In addition to this issue, the present study observed that there were significant observer discrepancies in the morphologic criteria of papillary thyroid carcinoma between Western and Eastern cytopathologists, which should be standardized. Furthermore, the borderline tumor category in thyroid tumor classification, which has recently been proposed by our group and by others, has not yet been established in the 2004 edition WHO tumor classification. Introduction of the borderline thyroid tumors into the thyroid tumor classification system requires establishment of cytological categories. A new reporting system for thyroid FNA cytology was proposed in this opinion paper, which adopted the classification of borderline lesions and addressed the recent progress made in molecular testing. This diagnostic system included new thyroid cytology terminologies and sub-classifications of the papillary carcinoma and follicular adenoma/follicular carcinoma lineages. Thus, these diagnostic categories will no longer be the grey zone or indeterminate, providing clear-cut instructions for clinical management of the patents with the aid of molecular tests.
胎儿细胞癌变：理论与实践
DOI：
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发表时间：
2007
期刊：
影响因子：
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作者：
Toru;Takano
通讯作者：
Takano
甲状腺胎儿细胞癌变：更好地理解甲状腺癌基因表达谱和基因组改变的假设
DOI：
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发表时间：
2004
期刊：
Endocr J 51(16)
影响因子：
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作者：
Yoshikawa M;Soda H;et al.;Takano T
通讯作者：
Takano T