KINETICS OF HEMOGLOBIN AND TRANSITION-STATE THEORY

KINETICS OF HEMOGLOBIN AND TRANSITION-STATE THEORY
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DOI:
10.1073/pnas.75.5.2108
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发表时间:
1978-01-01
影响因子:
11.1
通讯作者:
SZABO, A
SZABO, A
中科院分区:
综合性期刊1区
文献类型:
--
作者:
SZABO, A

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实验证据表明,血红蛋白中的协同性的方式表现动力学取决于配体的性质。NO,O2,CO和大体积异腈动力学的定性差异可以在基于过渡态理论的框架中以结构术语来理解。
Experimental evidence indicates that the way cooperativity in Hb is manifested kinetically depends on the nature of the ligand. The qualitative differences in the kinetics of NO, O2, CO and bulky isocyanides can be understood in structural terms in a framework based on transition state theory.