Spatial tuning of acoustofluidic pressure nodes by altering net sonic velocity enables high-throughput, efficient cell sorting.
Spatial tuning of acoustofluidic pressure nodes by altering net sonic velocity enables high-throughput, efficient cell sorting.
复制标题
通过改变净声速来空间调整声流体压力节点可实现高通量、高效的细胞分选。
DOI:
10.1039/c4lc01342e
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发表时间:
2015
期刊:
影响因子:
6.1
通讯作者:
Weinberger,LeorS
中科院分区:
文献类型:
--
作者:
Jung,Seung-Yong;Notton,Timothy;Fong,Erika;Shusteff,Maxim;Weinberger,LeorS
Particle sorting using acoustofluidics has enormous potential but widespread adoption has been limited by complex device designs and low throughput. Here, we report high-throughput separation of particles and T lymphocytes (600 μL min−1) by altering the net sonic velocity to reposition acoustic pressure nodes in a simple two-channel device. The approach is generalizable to other microfluidic platforms for rapid, high-throughput analysis.