Pathophysiology of pneumonia
Pathophysiology of pneumonia
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DOI：
10.1016/j.ccm.2004.10.013
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发表时间：
2005-03-01
影响因子：
5.7
通讯作者：
Torres, A
中科院分区：
文献类型：
--
作者：
Alcón, A;Fábregas, N;Torres, A
肺炎的发展需要病原体到达肺泡，宿主的防御被微生物的毒力或接种量所压倒。微生物的内源性来源是鼻携带者、鼻窦炎、口咽、胃或气管定植和血行播散。其他外部。污染源，如重症监护室工作人员、气溶胶或纤维支气管镜检查，必须视为意外。
The development of pneumonia requires that a pathogen reach the alveoli and that the host defenses are overwhelmed by microorganism virulence or by the inoculum size. The endogenous sources of microorganisms are nasal carriers, sinusitis, oropharynx, gastric, or tracheal colonization, and hematogenous spread. Other external. sources of contamination, such as intensive care unit workers, aerosols, or fibrobronchoscopy, must be considered as accidental.