Performance of dedicated emission mammotomography for various breast shapes and sizes
Performance of dedicated emission mammotomography for various breast shapes and sizes
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DOI：
10.1088/0031-9155/51/19/021
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发表时间：
2006-10-07
影响因子：
3.5
通讯作者：
Bowsher, J. E.
中科院分区：
文献类型：
--
作者：
Brzymialkiewicz, C. N.;Tornai, M. P.;Bowsher, J. E.
我们评估了乳房形状和大小以及病变位置对我们实验室开发的专用发射型乳房断层扫描系统的影响。半球形定位机架在对下垂的未压缩乳房进行采样时具有足够的灵活性。逼真的拟人躯干（包括手臂的上部）和乳房幻影提请注意使用独特的相机轨迹（轨道），而不是简单的圆形相机轨迹的必要性。我们已经实施了几种新颖的三维（3D）轨道，具有完全轮廓的旋转半径能力，用于补偿不同乳房形状和大小的定位需求。虽然一般轨道设计在两个不同乳房之间可以保持相同，但是绝对极倾斜范围和旋转半径范围可以变化。我们已经证明，使用具有增加的极坐标相机倾斜的3D轨道，对于大尺寸和小尺寸的乳房（325 ml至1060 ml），对于一系列内在对比度（病变中的活性浓度比乳房背景高3至10倍），胸壁附近的病变都可以可视化。总体而言，几乎完整的3D采集方案产生的图像数据具有相对较高的病变SNR和对比度，并且未压缩乳房形状的失真最小。
We evaluate the effect of breast shape and size and lesion location on a dedicated emission mammotomography system developed in our lab. The hemispherical positioning gantry allows ample flexibility in sampling a pendant, uncompressed breast. Realistic anthropomorphic torso ( which includes the upper portion of the arm) and breast phantoms draw attention to the necessity of using unique camera trajectories ( orbits) rather than simple circular camera trajectories. We have implemented several novel three-dimensional (3D) orbits with fully contoured radius-of-rotation capability for compensating for the positioning demands that emerge from different breast shapes and sizes. While a general orbit design may remain the same between two different breasts, the absolute polar tilt range and radius-of-rotation range may vary. We have demonstrated that using 3D orbits with increased polar camera tilt, lesions near the chest wall can be visualized for both large and small sized breasts (325 ml to 1060 ml), for a range of intrinsic contrasts ( three to ten times higher activity concentration in the lesion than breast background). Overall, nearly complete 3D acquisition schemes yield image data with relatively high lesion SNRs and contrasts and with minimal distortion of the uncompressed breast shape.