Design and fabrication of an injection tool for neuromuscular microstimulators.
Design and fabrication of an injection tool for neuromuscular microstimulators.
复制标题
神经肌肉微刺激器注射工具的设计和制造。
DOI：
10.1007/s10439-009-9739-5
复制
发表时间：
2009
影响因子：
3.8
通讯作者：
Loeb,GeraldE
中科院分区：
文献类型：
--
作者：
Kaplan,HiltonM;Loeb,GeraldE
将小植入物注射到体内精确定位的部位是外科医生或介入放射科医生通常承担的艰巨任务。我们设计、生产并测试了一种简单的工具，用于在门诊手术中植入BION™无线微刺激器。BION引起所需肌肉收缩的能力取决于它们在支配肌肉纤维的运动纤维附近的放置，从而提供了实现精确放置的要求和手段。植入物预装在由非导电聚合物制成的两件式插入工具的套管尖端。当工具被操纵到所需位置时，植入物产生试验刺激脉冲。通过在植入物上撤回套管来释放植入物，保留植入物电极相对于目标的相对位置并确定其期望的轴向取向，这对于包含运动传感器的植入物是重要的。迄今为止，BION插入工具已用于人体受试者的30多个BION植入物。
The injection of small implants into precisely localized sites within the body is a difficult task usually undertaken by surgeons or interventive radiologists. We have designed, produced and tested a simple tool for implanting BION™ wireless microstimulators as an outpatient office procedure. The ability of BIONs to elicit a desired muscle contraction depends on their placement near the motor fibers that innervate the muscle fibers, providing both the requirement and a means for achieving accurate placement. The implant is preloaded into the tip of the cannula of a two-piece insertion tool made from non-conductive polymers. Trial stimulation pulses are generated by the implant as the tool is manipulated into the desired position. The implant is released by withdrawing the cannula over the implant, preserving both the relative location of the implant’s electrodes with respect to the target and determining its desired axial orientation, which is important for implants containing motion sensors. The BION Insertion Tool has been used for over 30 BION implants in human subjects to date.