SQUID-detected MRI at 132 μT with T1-weighted contrast established at 10 μT-300 mT
SQUID-detected MRI at 132 μT with T1-weighted contrast established at 10 μT-300 mT
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DOI：
10.1002/mrm.20316
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发表时间：
2005-01-01
影响因子：
3.3
通讯作者：
Clarke, J
中科院分区：
文献类型：
--
作者：
Lee, SK;Mössle, M;Clarke, J
用超导量子干涉装置（SQUID）检测t -1加权预极化磁共振成像。在预极化和检测之间的可变场中有一个自旋演化周期，可以在1.7 ~ 300 mT的场中测量T-1；T，得到了琼脂糖凝胶样品在50年内频率上的分散曲线。与使用法拉第线圈检测的传统场循环方法相比，5.6 kHz的SQUID检测大大降低了场均匀性要求。这使得T-1弥散度测量可以很容易地与MRI相结合，因此T-1在广泛的领域可以用于组织对比。在10 muT和300 mT之间的4个不同视场中，凝胶幻影的t -1加权对比度图像在低视场中显示出明显的对比度增强。一种改进的反演恢复技术通过选择性地抑制特定低场T-1值的信号贡献进一步增强了对比度。出版于2004年Wiley-Liss， Inc。
T-1-weighted contrast MRI with prepolarization was detected with a superconducting quantum interference device (SQUID). A spin evolution period in a variable field between prepolarization and detection enabled the measurement of T-1 in fields between 1.7 muT and 300 mT; T, dispersion curves of agarose gel samples over five decades in frequency were obtained. SQUID detection at 5.6 kHz drastically reduces the field homogeneity requirements compared to conventional field-cycling methods using Faraday coil detection. This allows T-1 dispersion measurements to be easily combined with MRI, so that T-1 in a wide range of fields can be used for tissue contrast. Images of gel phantoms with T-1-weighted contrast at four different fields between 10 muT and 300 mT demonstrated dramatic contrast enhancement in low fields. A modified inversion recovery technique further enhanced the contrast by selectively suppressing the signal contribution for a specific value of the low-field T-1. Published 2004 Wiley-Liss, Inc.