Co-occurrence of 12-month mood and anxiety disorders and personality disorders in the US: results from the national epidemiologic survey on alcohol and related conditions
Co-occurrence of 12-month mood and anxiety disorders and personality disorders in the US: results from the national epidemiologic survey on alcohol and related conditions
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DOI：
10.1016/j.jpsychires.2004.05.004
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发表时间：
2005-01-01
影响因子：
4.8
通讯作者：
Huang, B
中科院分区：
文献类型：
--
作者：
Grant, BF;Hasin, DS;Huang, B
本研究的目的是确定DSM-IV人格障碍（pd）在美国人群中当前患有DSM-IV情绪和焦虑障碍的个体以及寻求此类情绪或焦虑障碍治疗的个体中的患病率和共发率。在国家酒精滥用和酒精中毒研究所2001-2002年全国酒精及相关疾病表皮病学调查（NESARC）中，对43,093名18岁及以上的个人进行了面对面访谈。计算比值比（or）来确定当前DSM-IV轴I和轴II疾病的患病率和相关性。情绪、焦虑和pd之间的关联均为正相关，且具有统计学意义。回避型和依赖型人格障碍与情绪障碍和焦虑障碍的相关性高于其他人格障碍。强迫症PD与情绪和焦虑障碍之间的联系是显著的，但要弱得多。偏执型和分裂型人格障碍与心境恶劣、躁狂症、惊恐障碍合并广场恐怖症、社交恐惧症和广泛性焦虑症的相关性最强，而戏剧型和反社会型人格障碍与躁狂症、惊恐障碍合并广场恐怖症的相关性最强。本研究结果强调需要进一步研究重叠症状学，引起关联的因素以及这些疾病共病时的治疗意义。(C) 2004 Elsevier Ltd.版权所有。
The objective of this study was to determine the prevalence and co-occurrence of DSM-IV personality disorders (PDs) among individuals with current DSM-IV mood and anxiety disorders in the US population and among individuals who sought treatment for such mood or anxiety disorders. Face-to-face interviews were conducted with 43,093 individuals, 18 years and older, in the National Institute on alcohol abuse and alcoholism's 2001-2002 National epiderniologic survey on alcohol and related conditions (NESARC). Odds ratios (ORs) were calculated to determine the prevalence and associations between current DSM-IV axis I and axis II disorders. Associations between mood, anxiety and PDs were all positive and statistically significant. Avoidant and dependent PDs were more strongly related to mood and anxiety disorders than other PDs. Associations between obsessive-compulsive PD and mood and anxiety disorders were significant, but much weaker. Paranoid and schizoid PDs were most strongly related to dysthymia, mania, panic disorder with agoraphobia, social phobia and generalized anxiety disorder, while histrionic and antisocial PDs were most strongly related to mania and panic disorder with agoraphobia. Results of this study highlight the need for further research on overlapping symptomatology, factors giving rise to the associations and the treatment implications of these disorders when comorbid. (C) 2004 Elsevier Ltd. All rights reserved.