Measures of sleep in rheumatologic diseases: Epworth Sleepiness Scale (ESS), Functional Outcome of Sleep Questionnaire (FOSQ), Insomnia Severity Index (ISI), and Pittsburgh Sleep Quality Index (PSQI).

Measures of sleep in rheumatologic diseases: Epworth Sleepiness Scale (ESS), Functional Outcome of Sleep Questionnaire (FOSQ), Insomnia Severity Index (ISI), and Pittsburgh Sleep Quality Index (PSQI).
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DOI:
10.1002/acr.20544
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发表时间:
2011-11
影响因子:
4.7
通讯作者:
Omachi, Theodore A.
Omachi, Theodore A.
中科院分区:
医学2区
文献类型:
--
作者:
Omachi, Theodore A.

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疲劳是与风湿性疾病(如系统性红斑狼疮和类风湿性关节炎)相关的主要症状,可能是疾病活动的直接表现,但这种疲劳也可能与睡眠障碍有关(1,2)。事实上,睡眠障碍在各种风湿性疾病中很常见(3-5)。这种睡眠障碍可能是由于疼痛,抑郁,缺乏锻炼,或皮质类固醇的使用(6-8)。睡眠质量也可能受到共病睡眠障碍的影响,如阻塞性睡眠呼吸暂停或不宁腿综合征,据报道,这些疾病在风湿性人群中的患病率很高(9-12)。睡眠障碍可能反过来影响功能障碍,降低疼痛阈值或损害免疫功能,从而导致与风湿病相关的发病率(13-15)。纤维肌痛和类风湿性关节炎的睡眠障碍比其他风湿性疾病受到了更多的关注,但即使在纤维肌痛和类风湿性关节炎中,也有许多与睡眠障碍的原因和结果相关的未回答的问题(3)。睡眠障碍的研究可能是繁重的,因为金标准直接测试,如多导睡眠图和多次睡眠潜伏期测试,既昂贵又需要研究对象投入大量时间。在活动受限和疼痛可能显著增加受试者负担的风湿病人群中,基于睡眠的研究可能会带来额外的挑战。因此,有强大的动力,利用病人报告的措施,在评估睡眠和睡眠相关的结果在风湿性疾病。
Fatigue is a major symptom associated with rheumatologic diseases such as systemic lupus erythematosis and rheumatoid arthritis and may be a direct manifestation of disease activity, but such fatigue may also be related to sleep disturbances (1, 2). Indeed, sleep disturbances are common in a variety of rheumatologic diseases (3–5). Such disturbed sleep may be due to pain, depression, lack of exercise, or corticosteroid usage (6–8). Sleep quality may also be impaired by comorbid sleep disorders, such as obstructive sleep apnea or restless leg syndrome, the prevalences of which are reported to be high in rheumatologic populations (9–12). Sleep disturbances may, in turn, impact functional disability, lower pain thresholds, or impair immune function and thus contribute to rheumatologic-associated morbidities (13–15). Sleep disturbances in fibromyalgia and rheumatoid arthritis have received relatively more attention than in other rheumatologic diseases, but even in fibromyalgia and rheumatoid arthritis, there are many unanswered questions related to the causes and outcomes of sleep disturbances (3).The study of sleep disturbances can be onerous because gold standard direct tests, such as polysomnography and multiple sleep latency testing, are both expensive and require considerable commitment of time from research subjects. Laboratory-based sleep studies may present an additional challenge in rheumatologic populations in whom mobility restriction and pain may significantly increase subject burden. Thus, there is strong impetus for utilizing patient-reported measures in assessing sleep and sleep-related outcomes in rheumatologic diseases.
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