ALCOHOL-CONSUMPTION AND THE RISK OF BREAST-CANCER
ALCOHOL-CONSUMPTION AND THE RISK OF BREAST-CANCER
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DOI：
10.1093/oxfordjournals.aje.a115419
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发表时间：
1989-11-01
影响因子：
5
通讯作者：
WEBSTER, LA
中科院分区：
文献类型：
--
作者：
CHU, SY;LEE, NC;WEBSTER, LA
为了检验饮酒和乳腺癌之间的关系，作者使用了疾病控制中心S癌症和类固醇激素研究的数据，这是一项基于人群的多中心病例对照研究。1981年8月至1982年12月，3498名年龄在20-54岁之间的美国新诊断乳腺癌患者和3157名年龄在20-54岁之间的随机抽取的女性被问及在过去五年中的饮酒情况。与不喝酒的女性相比，饮酒的女性患乳腺癌的风险为1.0(95%可信区间为0.9-1.2)。乳腺癌的风险并没有随着饮酒量的增加而显著增加：女性每周饮酒8-14、15-21和22或更多的风险估计分别为1.1、1.0和1.2。作者还发现，不同饮料类型或特定风险因素亚组之间没有显著差异。这些发现并不支持饮酒会增加乳腺癌风险的假设。
To examine the relation between alcohol consumption and breast cancer, the authors used data from the Centers for Disease Control''s Cancer and Steroid Hormone Study, a multicenter population-based case-control study. Between August 1981 and December 1982, 3,498 US women aged 20-54 years with newly diagnosed breast cancer and 3,157 women aged 20-54 years selected at random from the same geographic areas were asked about their consumption of alcoholic beverages during the previous five years. Women who drank any alcohol had a risk of breast cancer of 1.0 (95% confidence interval 0.9-1.2) compared with nondrinkers. The risk of breast cancer did not increase appreciably with increasing alcohol consumption: Risk estimates for women consuming 8-14, 15-21, and 22 or more drinks per week were 1.1, 1.0, and 1.2, respectively. The authors also found no notable differences by type of beverage or within specific risk factor subgroups. These findings do not support the hypothesis that alcohol consumption increases the risk of breast cancer.