Precision and accuracy in diffusion tensor magnetic resonance imaging.

Precision and accuracy in diffusion tensor magnetic resonance imaging.
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DOI:
10.1097/rmr.0b013e31821e56ac
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发表时间:
2010-04-01
期刊:
Topics in magnetic resonance imaging : TMRI
影响因子:
--
通讯作者:
Jones, Derek K
Jones, Derek K
中科院分区:
其他
文献类型:
--
作者:
Jones, Derek K

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本文综述了影响从扩散磁共振成像数据得出的定量指标的准确性和精密度的一些关键因素。重点介绍了从成像方案选择开始的研究流程,经过预处理和模型拟合,最后提取定量估计,为后续分析做好准备。其目的是为该领域的新手提供足够的知识,了解他们在这一过程中每个阶段的决定可能如何影响精密度和准确度,设计他们的研究/方法,并在临床上使用弥散张量磁共振成像。更具体地说,重点是提高准确度和精确度。我举例说明了一路上谨慎的选择会对从数据做出推断所需的样本量产生多大的影响。
This article reviews some of the key factors influencing the accuracy and precision of quantitative metrics derived from diffusion magnetic resonance imaging data. It focuses on the study pipeline beginning at the choice of imaging protocol, through preprocessing and model fitting up to the point of extracting quantitative estimates for subsequent analysis. The aim was to provide the newcomers to the field with sufficient knowledge of how their decisions at each stage along this process might impact on precision and accuracy, to design their study/approach, and to use diffusion tensor magnetic resonance imaging in the clinic. More specifically, emphasis is placed on improving accuracy and precision. I illustrate how careful choices along the way can substantially affect the sample size needed to make an inference from the data.