THE SELECTINS AND THEIR LIGANDS
THE SELECTINS AND THEIR LIGANDS
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DOI：
10.1016/0955-0674(94)90092-2
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发表时间：
1994-10-01
影响因子：
7.5
通讯作者：
BERTOZZI, CR
中科院分区：
文献类型：
--
作者：
ROSEN, SD;BERTOZZI, CR
选择素是碳水化合物结合蛋白或凝集素的一个家族，由于其参与白细胞和内皮细胞之间的广泛相互作用而引起了极大的兴趣。最新进展的亮点包括选择素参与炎症性疾病的实例列表的扩展，选择素碳水化合物特异性的进一步定义，以及其基于碳水化合物的配体的鉴定。
The selectins are a family of carbohydrate-binding proteins, or lectins, that have stimulated tremendous interest because of their involvement in a wide array of interactions between leukocytes and endothelial cells. Highlights of recent progress include an extension of the list of instances of selectin participation in inflammatory diseases, further definition of selectin carbohydrate specificities, and identification of their carbohydrate-based ligands.