MR SPECTROSCOPIC IMAGING OF COLLAGEN - TENDONS AND KNEE MENISCI
MR SPECTROSCOPIC IMAGING OF COLLAGEN - TENDONS AND KNEE MENISCI
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DOI：
10.1002/mrm.1910340502
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发表时间：
1995-11-01
影响因子：
3.3
通讯作者：
HERFKENS, RJ
中科院分区：
文献类型：
--
作者：
GOLD, GE;PAULY, JM;HERFKENS, RJ
与胶原相关的水分子具有较短的横向(T-2)弛豫时间。投影重建技术能够实现比传统技术短得多的回波时间(TE)，允许以5ms的T2和lt；5ms对组织进行成像。使用这些技术，传统的1，5-T磁共振人体成像系统可以直接成像正常志愿者和患者膝关节半月板和肌腱中的胶原相关水。长T-2抑制改善了这些结构与具有长T-2弛豫时间的周围组织之间的对比度。光谱成像提供了改进的脂/水配准以及有关化学成分和松弛时间的信息。肌腱和半月板的直接成像可以提供更多关于这些结构的信息，并为评估损伤和修复提供一种新的方法。
Water molecules associated with collagen have short transverse (T-2) relaxation times. Projection-reconstruction techniques are able to achieve an echo time (TE) much shorter than conventional techniques, allowing imaging of tissues with T-2 < 5 ms. Using these techniques, a conventional 1,5-T MRI human imaging system can directly image collagen-associated water from knee menisci and tendons in normal volunteers and patients. Long-T-2 suppression improves the contrast between these structures and the surrounding tissue with long-T-2 relaxation times. Spectroscopic imaging provides improved lipid/water registration and information about chemical composition and relaxation times. Direct imaging of tendons and menisci may provide more information about these structures and provide a new way to assess both injury and repair.