The critical DNA flanking sequences of a CpG oligodeoxynucleotide, but not the 6 base CpG motif, can be replaced with RNA without quantitative or qualitative changes in Toll-like receptor 9-mediated activity.
The critical DNA flanking sequences of a CpG oligodeoxynucleotide, but not the 6 base CpG motif, can be replaced with RNA without quantitative or qualitative changes in Toll-like receptor 9-mediated activity.
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CpG 寡脱氧核苷酸的关键 DNA 侧翼序列(但不是 6 碱基 CpG 基序)可以用 RNA 替换,而不会导致 Toll 样受体 9 介导的活性发生量或质的变化。
DOI:
10.1016/j.cellimm.2005.01.010
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发表时间:
2004
期刊:
影响因子:
--
通讯作者:
Snapper,CliffordM
中科院分区:
文献类型:
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作者:
Sen,Goutam;Flora,Michael;Chattopadhyay,Gouri;Klinman,DennisM;Lees,Andrew;Mond,JamesJ;Snapper,CliffordM