Effects of increasing depth of anaesthesia on phrenic nerve and hypoglossal nerve activity during the swallowing reflex in cats.
Effects of increasing depth of anaesthesia on phrenic nerve and hypoglossal nerve activity during the swallowing reflex in cats.
复制标题
增加麻醉深度对猫吞咽反射过程中膈神经和舌下神经活动的影响。
DOI：
10.1093/bja/57.2.208
复制
发表时间：
1985
影响因子：
9.8
通讯作者：
T. Yonezawa
中科院分区：
文献类型：
--
作者：
T. Nishino;Y. Honda;T. Kohchi;M. Shirahata;T. Yonezawa
本实验观察了10只猫在刺激喉上神经(SLN)诱发吞咽反射时，麻醉深度增加对膈神经(PN)活动和舌下神经(HN)活动的影响。刺激SLN诱发的吞咽反应总是伴随着Pn活动的特征短暂爆发和HN活动的大幅度爆发。Pn和HN活动的这些特征反应不受双侧迷走神经切断或神经肌肉阻断的影响，表明Pn和HN活动的特征反应可作为迷走神经切断和瘫痪动物吞咽反射的指标。在这类动物身上得到的结果表明，随着麻醉深度的增加，吞咽反射逐渐减弱。对HN活动的详细分析还表明，刺激SLN可引起三种不同的HN活动反应，这些反应对麻醉有不同的敏感性。然而，吞咽反射时观察到的特征反应对麻醉深度的增加最为敏感。
The effects of increasing depths of anaesthesia on phrenic nerve (PN) activity and hypoglossal nerve (HN) activity during the swallowing reflex elicited by stimulation of the superior laryngeal nerve (SLN) were investigated in 10 cats. Swallowing induced by SLN stimulation always coincided with a characteristic brief burst of PN activity and a large amplitude burst of HN activity. These characteristic responses of PN and HN activities were not influenced by either bilateral vagotomy or neuromuscular blockade, indicating that the characteristic responses of PN and HN activities can be used as indicators of the swallowing reflex in vagotomized and paralysed animals. The results obtained in such animals showed that increasing depth of anaesthesia depressed progressively the swallowing reflex. Detailed analysis of HN activity revealed also that SLN stimulation elicited three different responses of HN activity which had different sensitivities to anaesthesia. However, the characteristic response observed during the swallowing reflex was the most sensitive to increasing depth of anaesthesia.