Comparison of hydroxyapatite and beta tricalcium phosphate as bone substitutes after excision of bone tumors
Comparison of hydroxyapatite and beta tricalcium phosphate as bone substitutes after excision of bone tumors
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DOI：
10.1002/jbm.b.30136
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发表时间：
2005-01-15
影响因子：
3.4
通讯作者：
Endo, N
中科院分区：
文献类型：
--
作者：
Ogose, A;Hotta, T;Endo, N
报告了23名患者的长期结果和30名表现为骨肿瘤的患者的短期结果，这些患者分别接受了刮除或切除后植入羟基磷灰石(HA)或高纯度的β-磷酸三钙(β-TCP)。HA植入组和β-磷酸三钙植入组的平均随访期分别为97个月和26个月。X线片显示，除两例外，所有病例的HA都被吸收到宿主骨中；此外，没有观察到明显的HA生物降解的证据。1例患者在植入HA后出现晚期畸形。所有移植的β-磷酸三钙至少部分被吸收，并被新形成的骨取代。羟基磷灰石陶瓷与宿主骨之间的透光带消失所需的平均时间分别为17周和9.7周。高纯度的β-磷酸三钙在骨肿瘤的外科治疗中比透明质酸更具优势，因为它具有重塑和良好的骨传导性。(C)2004年威利期刊公司。
Long-term results are reported in 23 patients and short-term results in 30 patients presenting with bone tumors treated by curettage or resection followed by implantation of hydroxyapatite (HA) or highly purified beta-tricalcium phosphate (beta-TCP), respectively. Mean follow-up was 97 and 26 months in cases involving HA implantation and beta-TCP implantation, respectively. Radiographs revealed HA incorporation into host bone in all but two cases; moreover, no obvious evidence of HA biodegradation was observed. A single patient exhibited late deformity following implantation of HA. All grafted beta-TCP was, at least partially, absorbed and replaced by newly formed bone. The mean period required for the disappearance of radiolucent zones between the ceramics and host bone was 17 weeks in HA and 9.7 weeks in beta-TCP. Highly purified beta-TCP appears to be advantageous relative to HA for surgical intervention in bone tumors consequent to the nature of remodeling and superior osteoconductivity. (C) 2004 Wiley Periodicals, Inc.