Concentration and congener pattern of polychlorinated biphenyls in blubber and liver of Hubbs' beaked whale (Mesoplodon carlhubbsi), using a sulfoxide and an Ag-ION solid phase extraction cartridge as a simplified cleanup technique for biological samples
Concentration and congener pattern of polychlorinated biphenyls in blubber and liver of Hubbs' beaked whale (Mesoplodon carlhubbsi), using a sulfoxide and an Ag-ION solid phase extraction cartridge as a simplified cleanup technique for biological samples
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DOI：
10.1016/j.marpolbul.2016.09.051
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发表时间：
2016-12-15
影响因子：
5.8
通讯作者：
Matsuishi, Takashi
中科院分区：
文献类型：
--
作者：
Anezaki, Katsunori;Matsuda, Ayaka;Matsuishi, Takashi
我们进行了已知的第一次多氯联苯（PCBs）在哈布斯喙鲸的脂肪和肝脏中的浓度和模式的研究。采用Supeldean （TM）亚砜和Discovery (R) Ag-ION固相萃取盒对样品进行预处理，去除鲸油。脂肪和肝脏中PCB浓度分别为13000和7300 ng/g脂质。高毒性同系物，如二恶英样多氯联苯（DL）倾向于在肝脏中积聚。dl -多氯联苯在肝脏中的毒性当量（TEQ） （740 pg-TEQ/g脂质）高于脂肪中的毒性当量（74 pg-TEQ/g脂质）。鲸脂和肝脏样品显示，六氯联苯在同系物中占优势，而多氯联苯-153在同系物中占优势。一些同系物不成比例地积聚在鲸脂和肝脏中（PCB-28、52、74、99和118），而其他同系物则不存在（PCB-31、70和110）。这表明多氯联苯的代谢根据其特定的组成而不同。(C) 2016 Elsevier Ltd.版权所有。
We performed the first known study of polychlorinated biphenyls (PCBs) concentrations and patterns in the blubber and liver of a Hubbs' beaked whale. Samples were pretreated with Supeldean (TM) sulfoxide and Discovery (R) Ag-ION solid phase extraction cartridges to remove whale oil. PCB concentrations in the blubber and liver were 13,000 and 7300 ng/g lipid, respectively. Highly poisonous congeners such as dioxin-like (DL) PCBs tended to accumulate in the liver. The toxic equivalents (TEQ) of DL-PCBs in the liver (740 pg-TEO/g lipid) were higher than those in the blubber (74 pg-TEQ/g lipid). The blubber and liver samples showed that hexachlorinated biphenyls were dominant among homologues, and PCB-153 was dominant among congeners. Several congeners accumulated disproportionately in the blubber and the liver (PCB-28, 52, 74, 99, and 118), while others did not persist (PCB-31, 70, and 110). This indicates that PCBs are metabolized differently according to their specific composition. (C) 2016 Elsevier Ltd. All rights reserved.