Phylogeographic origin of Hokkaido house mice (Mus musculus) as indicated by genetic markers with maternal, paternal and biparental inheritance
Phylogeographic origin of Hokkaido house mice (Mus musculus) as indicated by genetic markers with maternal, paternal and biparental inheritance
复制标题
DOI：
10.1038/sj.hdy.6800761
复制
发表时间：
2006-02
期刊：
影响因子：
3.8
通讯作者：
Mie Terashima;Shunsuke Furusawa;N. Hanzawa;K. Tsuchiya;Agutinus Suyanto;K. Moriwaki;H. Yonekawa
中科院分区：
文献类型：
--
作者：
Mie Terashima;Shunsuke Furusawa;N. Hanzawa;K. Tsuchiya;Agutinus Suyanto;K. Moriwaki;H. Yonekawa
我们研究了来自日本群岛北部三分之一的家鼠(Mus Musculus Molossinus)的种内遗传变异，以获得可能塑造当前遗传多样性的小鼠殖民历史的证据。我们延长了之前对线粒体细胞色素b序列的采样，并增加了Y连锁Sry基因和核糖体RNA基因调查的信息。我们将北亚肌肉亚种群(包括肌肉支原体和大鼠)的线粒体单倍型特征区分为‘mus’，而将东南亚亚种群的线粒体单倍型区分为‘cas’(尽管这些小鼠在形态上与mus相似)。北海道南部和北部的MU和CAS类型在地理上有明显的划分。相反，在东北，MU和CAS类型穿插在一起，没有明确的地理划分。与mtDNA数据相反，所有被检查的北海道和东北小鼠都被发现具有一种独特的Y连锁Sry基因类型，这种基因是韩国和日本特有的。核rDNA探针的限制性内切酶切点分析表明，MUS和CAS类型在北海道和东北小鼠中的分布是一致的，分别为主要和次要成分。这些数据支持了之前的观点，即北海道和东北小鼠经历了中科院原生居民和通过南方路线到达的MUS新来者之间的基因杂交。MUS型的入侵可能与史前民族的到来相对应。然而，也有不同的解释，包括来自南部路线的MU和来自北部路线的CAS之间的基因混合。
We examined intraspecies genetic variation in house mice (Mus musculus molossinus) from the northern third of the Japanese Islands, in order to obtain evidence of the history of mouse colonization that might have shaped the current genetic diversity. We extended the previous sampling of mitochondrial cytochrome b sequence and added information from the Y-linked Sry gene and ribosomal RNA gene surveys. We distinguish mitochondrial haplotypes characteristic of the North Asian musculus subspecies group (involving M. m. musculus and M. m. molossinus) as ‘MUS’, and that of the Southeast Asian castaneus subspecies group as ‘CAS’(although the mice resemble MUS morphologically). There was a clear geographic partition of MUS and CAS types into southern and northern Hokkaido, respectively. Conversely, on Tohoku, the MUS and CAS types were interspersed without clear geographic subdivision. In contrast to the mtDNA data, all Hokkaido and Tohoku mice examined were found to possess a unique type for the Y-linked Sry gene, specific to Korea and Japan. Restriction site analysis of nuclear rDNA probe showed a consistent distribution of MUS and CAS types, as major and minor components, respectively, in the Hokkaido and Tohoku mice. These data support the previous notion that the Hokkaido and Tohoku mice experienced genetic hybridization between primary residents of CAS origin and MUS newcomers arriving via a southern route. The invasion of the MUS type could correspond with the evidence for arrival of prehistoric peoples. There are, however, alternative interpretations, including genetic admixture between MUS arriving by a southern route and CAS from a northern route.