Single channel studies on inactivation of calcium currents.
Single channel studies on inactivation of calcium currents.
复制标题
钙电流失活的单通道研究。
DOI：
10.1126/science.6330896
复制
发表时间：
1984
期刊：
影响因子：
--
通讯作者：
Brown,AM
中科院分区：
文献类型：
--
作者：
Lux,HD;Brown,AM
钙通道的失活归因于进入细胞的钙离子与钙通道的直接反应。对于一个单一的通道，这一假设预测的钙的量之间的相关性进入在开放或开放的突发和随后的关闭时间。没有发现这种相关性，并且排除了钙离子进入后产生失活的可能性。
Inactivation of calcium channels has been attributed to a direct reaction of calcium ions entering the cell with the calcium channel. For a single channel this hypothesis predicts a correlation between the amount of calcium entering during an opening or a burst of openings and the subsequent closed times. No such correlation was found, and the possibility that, upon entry, calcium ions produce inactivation is excluded.