Assessment of Sleep Impairment in Persistent Allergic Rhinitis Patients Using Polysomnography
Assessment of Sleep Impairment in Persistent Allergic Rhinitis Patients Using Polysomnography
复制标题
使用多导睡眠图评估持续性过敏性鼻炎患者的睡眠障碍
DOI：
10.1159/000317244
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发表时间：
2010-11
影响因子：
2.8
通讯作者：
Bachert, C.
中科院分区：
文献类型：
--
作者：
Meng, J.;Xuan, J.;Qiao, X.;Li, X.;Liu, S.;Lukat, K. F.;Zhang, N.;Bachert, C.
背景：尽管问卷调查显示变应性鼻炎(AR)患者的睡眠质量受损与症状之间存在关联，但迄今为止还没有ARIA指南对持续性变应性鼻炎(PER)患者的睡眠进行客观评估的报道。因此，本研究的目的是通过多导睡眠图(PSG)评估PER患者的睡眠障碍。方法：选择98例中重度鼻塞患者和30例健康志愿者作为研究对象。所有患者在夜间睡眠时都接受了PSG检查，以评估睡眠障碍的存在和严重程度。同时测量鼻腔最大吸气流量(PNIF)以评估鼻腔阻力。结果：PER患者与健康对照组在睡眠效率、觉醒指数、平均SaO2、最低SaO2、饱和度低于90%的时间和鼾声时间等大多数PSG参数上有统计学意义上的差异，尽管临床上并不明显。虽然呼吸暂停低通气指数在两组间无显著差异，但每组有17例(17.3%)患者有呼吸暂停低通气指数，而对照组无一例发生呼吸暂停低通气指数。T5SS评分较高的患者(12≤T5SS≤15)比T5SS评分较低的患者(8≤T5SS≤11)有更大的打鼾倾向。PER组PNIF明显低于对照组。唤醒指数与PNIF、平均SaO2和PNIF之间的相关性较弱。结论：与对照组相比，PER患者的PSG表现出轻微的变化。
Background: Although questionnaires have demonstrated an association between impairment of quality of sleep and symptoms in allergic rhinitis (AR) patients, to date there is no report of an objective assessment of sleep in patients with persistent allergic rhinitis (PER) as defined by ARIA guidelines. The aim of the present study was therefore to assess sleep disturbance in PER patients by polysomnography (PSG). Methods: Ninety-eight PER patients with moderate-to-severe nasal obstruction and 30 healthy volunteers were included in the study. All patients underwent PSG during nocturnal sleep to assess the presence and severity of sleep disorders. Peak nasal inspiratory flow (PNIF) was also measured to assess nasal resistance. Results: There were statistically significant, though clinically modest, differences between PER patients and healthy controls in most PSG parameters including sleep efficiency, arousal index, average SaO2, lowest SaO2, time spent with a saturation below 90%, and snoring time. Although the apnea-hypopnea index (AHI) was not significantly different between the 2 groups, 17 subjects (17.3%) in the PER group but none of the control subjects had an AHI >5. Patients with higher T5SS scores (12 ≤ T5SS ≤ 15) had a greater tendency to snore than did patients with lower scores (8 ≤ T5SS ≤ 11). Finally, PNIF in the PER group was significantly lower than in the control group. Weak correlations between the arousal index and PNIF, average SaO2, and PNIF were found. Conclusion: PSG showed modest changes in PER patients versus control subjects.
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影响因子：
6.1
作者：
M. Tashiro;H. Mochizuki;Kentaro Iwabuchi;Yumiko Sakurada;M. Itoh;Takehiko Watanabe;K. Yanai
通讯作者：
M. Tashiro;H. Mochizuki;Kentaro Iwabuchi;Yumiko Sakurada;M. Itoh;Takehiko Watanabe;K. Yanai
DOI：
10.1016/s1081-1206(10)62449-0
发表时间：
2000-08
期刊：
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
影响因子：
--
作者：
A. Wilson;O. J. Dempsey;E. Sims;B. Lipworth
通讯作者：
A. Wilson;O. J. Dempsey;E. Sims;B. Lipworth
影响因子：
4.2
作者：
H. M. Paisner
通讯作者：
H. M. Paisner
影响因子：
2.8
作者：
T. Craig;C. Mende;K. Hughes;S. Kakumanu;E. Lehman;V. Chinchilli
通讯作者：
T. Craig;C. Mende;K. Hughes;S. Kakumanu;E. Lehman;V. Chinchilli
影响因子：
7.2
作者：
M. Holmström;G. Scadding;V. Lund;Y. Darby
通讯作者：
M. Holmström;G. Scadding;V. Lund;Y. Darby