Analysis of Multilocus Sequence Typing for Identification of Leptospira Isolates in Brazil
Analysis of Multilocus Sequence Typing for Identification of Leptospira Isolates in Brazil
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DOI：
10.1128/jcm.01119-11
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发表时间：
2011-11-01
影响因子：
9.4
通讯作者：
Galloway, R. L.
中科院分区：
文献类型：
--
作者：
Romero, E. C.;Blanco, R. M.;Galloway, R. L.
采用多位点序列分型（MLST）和传统血清分型对101株钩端螺旋体进行检测。MLST将分离株分为4个序列型（STs），血清分型将分离株分为6个血清群。两株分离菌株经MLST分析，部分基因无法产生产物。对巴西罕见的人类分离株，MLST比血清分型更具歧视性。
A collection of 101 Leptospira isolates was tested by multilocus sequence typing (MLST) and by traditional serotyping. MLST divided the isolates into 4 sequence types (STs), while serotyping classified them into 6 serogroups. Two isolates failed to generate products for some genes by MLST. MLST was less discriminatory than serotyping for uncommonly occurring isolates from humans in Brazil.