Sequence of improvement in depressive symptoms across cognitive therapy and pharmacotherapy

Sequence of improvement in depressive symptoms across cognitive therapy and pharmacotherapy
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DOI:
10.1016/j.jad.2007.12.227
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发表时间:
2008-09-01
影响因子:
6.6
通讯作者:
Beck, Aaron T.
Beck, Aaron T.
中科院分区:
医学2区
文献类型:
--
作者:
Bhar, Sunil S.;Gelfand, Lois A.;Beck, Aaron T.

文献摘要

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背景:作者研究了接受认知疗法(CT)或药物疗法(PT)治疗的重度抑郁症患者的认知和植物症状的改善模式。方法:门诊诊断为重度抑郁症的患者(180例)随机接受CT或PT治疗。在16周的治疗期间,在基线和定期使用贝克抑郁量表- ii测量重度抑郁症的认知和植物症状。结果:多元层次线性模型显示,CT和pt中认知症状和植物症状随时间的变化模式相同。局限性:自我报告的测量可能不够具体,无法捕捉到植物症状和认知症状改善的细微差异。结论:这些结果与Beck的[Beck, a.t., 1994,11月]一致。认知与理论[给编辑的信]。拱门。精神病学,41,1112-1114。假设CT和PT有相似的作用部位,当靶向时,会导致认知和营养特征的变化。(C) 2007 Elsevier B.V.版权所有
Background: The authors examined the patterns of improvement in cognitive and vegetative symptoms of major depression in individuals treated with cognitive therapy (CT) or pharmacotherapy (PT).Method: Outpatients diagnosed with major depressive disorder (n = 180) were randomized to receive either CT or PT. Cognitive and vegetative symptoms of major depression were measured by the Beck Depression Inventory-II at baseline and regularly throughout 16 weeks of treatment.Results: Multivatiate hierarchical linear modeling demonstrated the same patterns of change over time for cognitive and vegetative symptoms within CT and within PT.Limitations: Self-report measures may not be sufficiently specific to capture subtle differences in improvements between vegetative and cognitive symptoms.Conclusions: These results are consistent with Beck's [Beck, A.T., 1994, November. Cognition and theory [Letter to the editor]. Arch. Gen. Psychiatry 41, 1112-1114.] hypothesis that CT and PT have a similar site of action, which when targeted, results in changes in both cognitive and vegetative features. (C) 2007 Elsevier B.V. All rights reserved.