Simultaneous positron emission tomography and magnetic resonance imaging for the detection and characterisation of liver lesions in patients with colorectal cancer: A pictorial review
Simultaneous positron emission tomography and magnetic resonance imaging for the detection and characterisation of liver lesions in patients with colorectal cancer: A pictorial review
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DOI：
10.1111/1754-9485.12936
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发表时间：
2019-10
影响因子：
1.6
通讯作者：
E. Yeoh;K. Miles
中科院分区：
文献类型：
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作者：
E. Yeoh;K. Miles
结直肠癌患者经常接受诊断成像，以分期转移疾病的程度并评估对治疗的反应。成像通常通过诊断性对比增强CT或FDG-PET/CT联合进行。然而，最近的研究表明，由于MRI优越的软组织对比度，联合FDG-PET/MRI在肿瘤学成像中具有良好的优势。在确定结直肠癌患者的治疗方案时，肝内和肝外病变的程度都很重要，FDG-PET/CT和专用肝脏成像通常都是必需的。FDG-PET/MRI具有单次检查的优点，可以在与专门的肝脏MRI成像相似的时间内完成。这改善了患者的方便性和PET和MRI成像之间的解剖联合配准，并提供了潜在的成本效益。FDG-PET/MRI的诊断优势包括同时确定局部肝脏病变的特征，排除肝外疾病，检测额外的肝转移和肝外疾病，以及对治疗反应的多参数评估。这篇图片回顾重点介绍了这些好处的例子。
Patients with colorectal cancer undergo frequent diagnostic imaging to stage the extent of metastatic disease and assess response to treatment. Imaging is typically via diagnostic contrast‐enhanced CT or combined FDG‐PET/CT. However, recent research has demonstrated promising benefits of combined FDG‐PET/MRI in oncologic imaging due to the superior soft‐tissue contrast of MRI. The extent of both intrahepatic and extrahepatic disease is important in establishing treatment options for colorectal cancer patients, and FDG‐PET/CT and dedicated liver imaging are often both required. FDG‐PET/MRI offers the advantage of a single examination which can be completed within a similar duration as dedicated liver MRI imaging. This improves patient convenience and anatomical co‐registration between PET and MRI imaging and provides a potential cost benefit. The diagnostic benefits of FDG‐PET/MRI include the simultaneous characterisation of focal liver lesions, exclusion of extrahepatic disease, the detection of additional hepatic metastases and extrahepatic disease, and the multi‐parametric assessment of treatment response. This pictorial review highlights examples of these benefits.