Associations between short-term exposure of PM2.5 constituents and hospital admissions of cardiovascular diseases among 18 major Chinese cities
Associations between short-term exposure of PM2.5 constituents and hospital admissions of cardiovascular diseases among 18 major Chinese cities
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DOI：
10.1016/j.ecoenv.2022.114149
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Pei Gao
中科院分区：
文献类型：
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作者：
Yi Zhang;Wei Li;Ning Jiang;Shudan Liu;Jingyuan Liang;Nana Wei;Yuanyuan Liu;Yaohua Tian;Da Feng;Jinxi Wang;Chen Wei;Xun Tang;Tiantian Li;Pei Gao
Previous studies showed different risk effects on exposure of fine particulate matter (PM 2.5 ) mass for cardiovascular disease (CVD) globally, which is likely due to different constituents of PM 2.5 . This study aimed to investigate the association between short-term exposure of PM 2.5 constituents and hospital admissions of CVD. Daily counts of city-specific hospital admissions for CVD in 18 cities in China between 2014 and 2017 were extracted from the national Urban Employee Basic Medical Insurance database and the Beijing Municipal Commission of Health and Family Planning Information Center database. Directly measured PM 2.5 constituents, including ions and polycyclic aromatic hydrocarbons, were collected by the Chinese Environmental Public Health Tracking system. We used the time-stratified case-crossover design to estimate the association between PM 2.5 constituents and hospital admissions of CVD. Concentrations of ions accounted for the majority of the detected constituents. Excess risk (ER) of average ions concentrations for CVD was highest as 2.30% (95% CI: 1.62–2.99%) for NH 4 + , whose major sources are residential and agricultural emissions. This was followed by 1.85% (1.30–2.41%) for NO 3 - (generally from vehicles), 0.95% (0.28–1.63%) for SO 4 2- (often from fossil fuel burning) respectively. The association for ions were generally consistent with ischemic heart disease (IHD) and ischemic stroke, e.g., NH 4 + was associated with IHD (2.50%; 1.52–3.48%) and ischemic stroke (1.77%; 0.65–2.9%). For polycyclic aromatic hydrocarbons (PAHs), mainly from coal and vehicle-related oil combustion, the constituents were all associated with ischemic stroke but not for IHD. The ER for ischemic stroke was highest at 1.69% (0.99–2.39%) for indeno (123-cd) pyrene. Thus, in terms of the subtypes of CVD, the risks of hospital admissions varied with exposure to different PM 2.5 constituents. Exposed to NH 4 + had the highest risk to IHD and ischemic stroke, whereas PAHs were predominately associated with ischemic stroke only. • Certain ions were consistently associated with CVD, IHD and ischemic stroke. • PAHs were predominately associated with ischemic stroke only. • Exposed to NH 4 + brought the highest risk of CVD.
