Diagnosis of cancer in humans by 1H NMR of tissue biopsies
Diagnosis of cancer in humans by 1H NMR of tissue biopsies
复制标题
通过组织活检的 1H NMR 诊断人类癌症
DOI：
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发表时间：
1998
期刊：
影响因子：
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通讯作者：
D. E. Blandford
中科院分区：
文献类型：
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作者：
I. Smith;D. E. Blandford
我们描述了通过组织活检的~1H核磁共振诊断人类癌症的方法学，具有高水平的准确性、敏感性和特异性。这种方法通过仔细的样品准备和对光谱数据的多元分析而变得稳健和准确。给出了前列腺癌和卵巢癌的诊断实例。这些方法在体内非侵入性使用的潜力被证明是非常积极的。关键词：方法学，前列腺，卵巢。
We describe methodology for the diagnosis of human cancer, at high levels of accuracy, sensitivity, and specificity, by 1H NMR of tissue biopsies. This method is made robust and accurate by careful specimen preparation, and by multivariate analysis of spectral data. Examples are presented for the diagnosis of cancer of the prostate gland and the ovary. The potential for use of these methods noninvasively, in vivo, is shown to be very positive.Key words: methodology, prostate gland, ovary.