Effect of Light and Melatonin and Other Melatonin Receptor Agonists on Human Circadian Physiology.

Effect of Light and Melatonin and Other Melatonin Receptor Agonists on Human Circadian Physiology.
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光,褪黑激素以及其他褪黑激素激动剂对人昼夜生理学的影响。

DOI:
10.1016/j.jsmc.2015.08.001
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发表时间:
2015-12
影响因子:
2.8
通讯作者:
Burgess HJ
Burgess HJ
中科院分区:
其他
文献类型:
--
作者:
Emens JS;Burgess HJ

文献摘要

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昼夜节律(生物钟)时间对心理健康、身体健康和健康行为有着深远的影响。本综述重点关注如何使用光、褪黑激素和其他褪黑激素受体激动剂药物来改变昼夜节律失调患者的昼夜节律。简要概述了人类昼夜节律系统,然后讨论了可能影响治疗选择的患者特征和安全考虑因素。回顾了光治疗、避光、外源性褪黑激素和其他褪黑激素受体激动剂的重要特征,以及光和褪黑激素治疗的一些实际问题。
Circadian (body clock) timing has a profound influence on mental health, physical health, and health behaviors. This review focuses on how light, melatonin and other melatonin receptor agonist drugs can be used to shift circadian timing in patients with misaligned circadian rhythms. A brief overview of the human circadian system is provided, followed by a discussion of patient characteristics and safety considerations that can influence the treatment of choice. The important features of light treatment, light avoidance, exogenous melatonin and other melatonin receptor agonists are reviewed, along with some of the practical aspects of light and melatonin treatment.