Simulation analysis of rectifying microfluidic mixing with field-effect-tunable electrothermal induced flow

Simulation analysis of rectifying microfluidic mixing with field-effect-tunable electrothermal induced flow
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场效应可调电热诱导流整流微流混合仿真分析

DOI:
10.1002/elps.201700234
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发表时间:
2018-03-01
期刊:
影响因子:
2.9
通讯作者:
Li, You
Li, You
中科院分区:
生物学3区
文献类型:
--
作者:
Liu, Weiyu;Ren, Yukun;Li, You

文献摘要

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We report herein field-effect control on in-phase electrothermal streaming from a theoretical point of view, a phenomenon termed alternating-current electrothermal-flow field effect transistor (ACET-FFET), in the context of a new technology for handing analytes in microfluidics. Field-effect control through a gate terminal endows ACET-FFET the ability to generate arbitrary symmetry breaking in the transverse vortex flow pattern, which makes it attractive for mixing microfluidic samples. A computational model is developed to study the feasibility of this new microfluidic device design for micromixing. The influence of various parameters on developing an efficient mixer is investigated, and an integrated layout of discrete electrode array is suggested for achieving high-throughput mixing. Our physical demonstration with field-effect electrothermal flow control using a simple electrode structure proves invaluable for designing active micromixers for modern micro total analytical system.