Meta-analysis of the comorbidity rate of allergic rhinitis and asthma in Chinese children
Meta-analysis of the comorbidity rate of allergic rhinitis and asthma in Chinese children
复制标题
中国儿童变应性鼻炎和哮喘合并症发生率的Meta分析
DOI：
10.1016/j.ijporl.2018.02.001
复制
发表时间：
2018-04-01
影响因子：
1.5
通讯作者：
Wei, Ping
中科院分区：
文献类型：
--
作者：
Kou, Wei;Li, Xuelei;Wei, Ping
目的：过敏性鼻炎（AR）和哮喘经常同时发生，是儿童气道最常见的两种炎症性疾病。调查儿童哮喘和 AR 合并症的大规模研究很少。因此，我们进行了一项荟萃分析来描述中国儿童哮喘和 AR 的共病率。方法：我们从 Pubmed、Science、Springer、Elsevier、Embase、BMJ 以及万方数据、维普、CBM 和 CNKI 等四个中国生物医学数据库中检索相关研究。从这些单独的研究中，提取并汇总了中国儿童哮喘和 AR 的共发病率，以生成 R 版本 3.2.3 中的总结效应估计。结果：荟萃分析包括 25 项横断面研究。结果表明，我国AR儿童哮喘发病率为35.01%（95% CI：32.32%-37.70%），哮喘儿童AR发病率为54.93%（95% CI：53.05%-56.80%）。结论：我国儿童AR与哮喘共病率较高。据统计，哮喘儿童的 AR 患病率高于 AR 儿童的哮喘患病率。 AR 和哮喘的共发病率表明呼吸科医生和耳鼻喉科医师提高对这两种情况的认识和治疗的重要性。
Objectives: Allergic rhinitis (AR) and asthma often occur concomitantly and are the two most common inflammatory conditions of the airways in children. Large-scale studies investigating the comorbidity of asthma and AR in children are rare. So, we performed a meta-analysis to describe the comorbidity rate of asthma and AR in Chinese children.Methods: We retrieved related studies from Pubmed, Science, Springer, Elsevier, Embase, BMJ, and four Chinese biomedical databases, including Wanfang Data, VIP, CBM, and CNKI. From these individual studies, the co-morbidity rate of asthma and AR in Chinese children was extracted and pooled to generate summary effect estimates in R version 3.2.3.Results: The meta-analysis included 25 cross-sectional studies. The results indicated that in China, the incidence of asthma in children with AR is 35.01% (95% CI: 32.32%-37.70%) and the incidence of AR in children with asthma is 54.93% (95% CI: 53.05%-56.80%).Conclusions: The comorbidity of AR and asthma is high in Chinese children. Statistically, the prevalence of AR was higher in children with asthma, as opposed to the prevalence of asthma in children with AR. The co-morbidity rate of AR and asthma signifies the importance of improving the recognition and treatment under both conditions by respiratory physicians and otolaryngologists.