Relevance of claudication pain distance in patients with peripheral arterial occlusive disease.
Relevance of claudication pain distance in patients with peripheral arterial occlusive disease.
复制标题
外周动脉闭塞性疾病患者跛行疼痛距离的相关性。
DOI：
10.1024/0301-1526.28.1.25
复制
发表时间：
1999
期刊：
影响因子：
--
通讯作者：
A. Wiesemann
中科院分区：
文献类型：
--
作者：
U. Müller;I. Kirchberger;A. Wiesemann
背景
确定无痛和最大步行距离是PAOD患者血管检查的常规程序的一部分。然而，还不清楚这两个参数中的哪一个在确定患者的病理状况方面更相关。
患者和方法
对150例稳定性间歇性跛行患者在3.0km/h、12%倾斜度的踏车上测定跛行疼痛距离（CPD）和最大疼痛距离（MPD）。将结果与血管造影结果、多普勒压力值和主观生活质量（PAVK-86-问卷）进行比较。
结果
平均无痛步行距离为89 +/- 71 m，最大步行距离为198 +/- 141 m。步行距离和PAOD的血管造影范围之间没有相关性。仅MPD与踝部收缩期多普勒压力和跛行腿踝/臂压力指数相关（r = 0.16，p < 0.05和r = 0.20，p < 0.01）。CPD和MDP均对患者的生活质量有显著影响（CPD：r =-0.41，p = 0.001; MPD：r =-0.47，p = 0.001）。在多元回归分析中，除了体重指数，MPD被认为是病理相关的生活质量维度疼痛，投诉和功能状态的最大预测因子。
结论
最大步行距离与PAOD客观和主观评价标准的相关性优于无痛步行距离。因此，就疾病的阶段和患者的生活质量而言，该参数具有更大的重要性。这一事实值得在日常临床实践和进行临床试验时得到更多的关注。
BACKGROUND
Determination of both the pain-free and the maximum walking distances is part of a routine program in the angiological examination of patients with PAOD. It is however as yet not clear which of these two parameters is more relevant in determining a patient's pathological condition.
PATIENTS AND METHODS
In 150 patients with stable intermittent claudication, the claudication pain distance (CPD) and the maximum pain distance (MPD) were determined on a treadmill at 3.0 km/h and 12% inclination. The results were compared with the angiographic findings, the Doppler pressure values and the subjective quality of life (PAVK-86-Questionnaire).
RESULTS
The average pain-free walking distance was 89 +/- 71 m, and the maximum walking distance was 198 +/- 141 m. There was no correlation between both walking distances and the angiographic extent of PAOD. Only the MPD correlated with the ankle systolic Doppler pressure and the ankle/brachial pressure index of the claudicating leg (r = 0.16, p < 0.05 and r = 0.20, p < 0.01). Both the CPD and the MDP had a significant influence on the life quality of the patients (CPD: r = -0.41, p < 0.001; MPD: r = -0.47, p < 0.001). In the multiple regression analysis, beside the body mass index, the MPD was found to be the greatest predictor for the pathologically relevant quality of life dimensions pain, complaints and functional status.
CONCLUSIONS
The maximum walking distance correlated in a better way than pain-free walking distance with the objective and subjective assessment criteria of PAOD. Therefore, as regards the stage of the disease and the life quality of the patient, this parameter has a greater importance. This fact deserves to receive greater attention in everyday clinical practice and when conducting clinical trials.