WHAT PSYCHOLOGICAL PROCESS MEDIATES FEEDING EVOKED BY ELECTRICAL-STIMULATION OF THE LATERAL HYPOTHALAMUS
WHAT PSYCHOLOGICAL PROCESS MEDIATES FEEDING EVOKED BY ELECTRICAL-STIMULATION OF THE LATERAL HYPOTHALAMUS
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DOI：
10.1037/0735-7044.105.1.3
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发表时间：
1991-02-01
影响因子：
1.9
通讯作者：
VALENSTEIN, ES
中科院分区：
文献类型：
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作者：
BERRIDGE, KC;VALENSTEIN, ES
由于对下丘脑外侧区（ESLH）的电刺激可以引起进食和奖励，因此大多数研究人员得出的结论是，刺激不会引起与饥饿相关的厌恶信号。相反，有人假设 ESLH 通过唤起愉悦的味觉来启动摄入。在表现出刺激相关进食的老鼠身上直接体验到了这种享乐假说。与预测相反，我们发现 ESLH 期间的味觉反应（张嘴、伸出舌头等）比享乐更令人厌恶。有人认为，刺激通过增强外部刺激的显着性而非享乐价值来影响行为。这种激励显着假说的优点在于，它避免了在刺激过程中假设享乐感官体验的需要，并且它可以解释当条件改变时诱发进食如何转变为其他行为。
Because electrical stimulation of the lateral hypothalamus (ESLH) can elicit both feeding and reward, most investigators have concluded that stimulation does not evoke the aversive cues associated with hunger. It has been hypothesized, instead, that ESLH primes ingestion by evoking pleasurable taste sensations. A direct taste of this hedonic hypothesis was undertaken in rats that showed stimulus-bound feeding. Contrary to the prediction, it was found that the taste reactions (gapes, tongue protrusions, etc.) during ESLH were more aversive than hedonic. It is suggested that the stimulation influences behavior by potentiating the salience, but not the hedonic value, of external stimuli. The advantages of this incentive salience hypothesis are that it circumvents the need to postulate a hedonic sensory experience during stimulation and that it can explain how evoked feeding may switch to other behaviors when conditions are altered.