How common are psychotic and bipolar disorders? A 50-year follow-up of the Lundby population
How common are psychotic and bipolar disorders? A 50-year follow-up of the Lundby population
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DOI：
10.1080/08039480903009118
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发表时间：
2009-01-01
影响因子：
1.8
通讯作者：
Nettelbladt, Per
中科院分区：
文献类型：
--
作者：
Bogren, Mats;Mattisson, Cecilia;Nettelbladt, Per
背景资料：其目的是提出所有精神病和双相（BP）障碍的患病率在总的一般人群（n=3563），这是从1947年至1997年。材料与方法：最佳估计的共识DSM-IV诊断，从访谈，病例记录，登记册和关键线人的数据支持，进行了评估。分别计算了1947 ~ 1997年的期间患病率和1997年的终生患病率。结果如下：每100人的患病率为：任何精神病或BP障碍为4.24，非情感性精神病（NAP）障碍为2.25，与一般医学状况（GMC）相关的精神病（GMC）为0.76，情感性精神病（AP）障碍为0.62，物质诱导的精神病（SIP）障碍为0.59。每100人的LTP为：任何精神病或BP障碍为2.82，NAP障碍为1.38，与GMC相关的精神病障碍为0.54，SIP障碍为0.48，AP障碍为0.42。精神分裂症是最高的特异性诊断，患病率为1.43/100，LTP为0.84/100。与GMC、SIP障碍、精神分裂症和妄想障碍相关的精神病性障碍的LTP分别高于最近的社区研究，而短暂精神病性障碍、精神分裂症样障碍和AP障碍的LTP分别较低。然而，调查结果与芬兰精神病研究1的估计值大致雅阁。结论：研究结果表明，精神障碍是常见的社区，并应被视为一个主要的公共卫生问题。
Background: The purpose was to present the prevalence of all psychotic and bipolar (BP) disorders in a total general population (n=3563), which has been followed from 1947 to 1997. Materials and Methods: Best-estimate consensus DSM-IV diagnoses, supported by data from interviews, case notes, registers and key-informants, were assessed. The period prevalence from 1947 to 1997 and the lifetime prevalence (LTP) in 1997, respectively, was calculated. Results: The period prevalence per 100 was: 4.24 for any psychotic or BP disorder, 2.25 for non-affective psychotic (NAP) disorder, 0.76 for psychotic disorder related to a general medical condition (GMC), 0.62 for affective psychotic (AP) disorder and 0.59 for substance-induced psychotic (SIP) disorder. The LTP per 100 was: 2.82 for any psychotic or BP disorder, 1.38 for NAP disorder, 0.54 for psychotic disorder related to a GMC, 0.48 for SIP disorder and 0.42 for AP disorder. The specific diagnosis with the highest period prevalence 1.43 per 100 and LTP 0.84 per 100, respectively, was schizophrenia. The LTP of psychotic disorder related to a GMC, SIP disorder, schizophrenia and delusional disorder, respectively, was higher than in most recent community studies while the LTP of brief psychotic disorder, schizophreniform disorder and AP disorder, respectively, was lower. However, the findings were in approximate accord with the estimates in the Psychoses in Finland (PIF) Study 1. Conclusions: The findings suggest that psychotic disorders are common in the community, and should be considered a major public health concern.