The effects of caffeine and stress on blood pressure in individuals with and without a family history of hypertension.
The effects of caffeine and stress on blood pressure in individuals with and without a family history of hypertension.
复制标题
咖啡因和压力对有或没有高血压家族史的个体血压的影响。
DOI：
10.1111/j.1469-8986.1987.tb00269.x
复制
发表时间：
1987
期刊：
影响因子：
3.7
通讯作者：
D. Shapiro
中科院分区：
文献类型：
--
作者：
W. Greenberg;D. Shapiro
在一项随机双盲交叉设计中，对 36 名男性咖啡因使用者（其中一半有高血压家族史，一半没有高血压家族史）中比较了两种剂量的咖啡因（125 毫克、250 毫克）与安慰剂剂量（3 毫克）的效果。在休息、心算任务和恢复期间记录收缩压、心率和呼吸。在休息和精神压力条件下，与安慰剂相比，两种剂量的咖啡因平均使收缩压增加 6.7 微升。 125 mg 和 250 mg 剂量的效果没有显着差异。咖啡因和精神压力的升压作用以累加的方式结合在一起。在所有情况下，有高血压家族史的个体的收缩压水平均显着升高，但并不是特别对咖啡因产生反应。结果与之前在未接触咖啡因的受试者中报告的结果相当。
The effects of two doses of caffeine (125 mg, 250 mg) were compared to a placebo dose (3 mg) in a randomized double-blind cross-over design in 36 male caffeine users, half with and half without a family history of hypertension. Systolic blood pressure, heart rate, and respiration were recorded during rest, a mental arithmetic task, and recovery periods. I inter both resting and mental stress conditions, the two doses of caffeine on the average increased systolic pressure by 6.7 mini In compared to the placebo. The effects for the 125 me and 250 mg doses did not differ significantly. The pressor effects of caffeine and mental stress combined in an additive fashion. Systolic blood pressure levels were significantly greater in individuals with a family history of hypertension across all conditions, but not specifically in response to caffeine. The results arc comparable to those previously reported in caffeine-naive subjects.