Reproducibility and reliability of atherosclerotic plaque volume measurements in peripheral arterial disease with cardiovascular magnetic resonance
Reproducibility and reliability of atherosclerotic plaque volume measurements in peripheral arterial disease with cardiovascular magnetic resonance
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DOI：
10.1080/10976640600843330
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发表时间：
2007-01-01
影响因子：
6.4
通讯作者：
Kramer, Christopher M.
中科院分区：
文献类型：
--
作者：
Isbell, David C.;Meyer, Craig H.;Kramer, Christopher M.
量化外周血管系统中动脉粥样硬化斑块的高分辨率、非侵入性方法可能具有重要的临床和研究效用。使用 1.5T CMR 扫描仪对 17 名患有外周动脉疾病 (PAD) 的患者进行了研究。测量股浅动脉中的动脉粥样硬化斑块体积，并确定观察者间、观察者内和重测变异性。研究了 19 艘船，每艘船的平均采集时间为 13.1 分钟。平均斑块体积为 7.27 +/- 3.73 cm(3)。观察者内组内相关性为 R = 0.997，观察者间相关性为 R = 0.987，重测重现性为 R = 0.996。因此，PAD 中斑块体积的高分辨率测量是可靠且可重复的。
A high resolution, noninvasive approach to quantify atherosclerotic plaque in the peripheral vasculature could have significant clinical and research utility. Seventeen patients with peripheral arterial disease (PAD) were studied in a 1.5T CMR scanner. Atherosclerotic plaque volume in the superficial femoral artery was measured and interobserver, intraobserver, and test-retest variability determined. Nineteen vessels were studied with mean acquisition time of 13.1 minutes per vessel. Mean plaque volume was 7.27 +/- 3.73 cm(3). Intra-observer intraclass correlation was R = 0.997, inter-observer was R = 0.987, and test-retest reproducibility was R = 0.996. Thus, high resolution measurement of plaque volume in PAD is reliable and reproducible.